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923 results

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Page 1
Genomic instability in mice lacking histone H2AX.
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A. Celeste A, et al. Among authors: chen ht. Science. 2002 May 3;296(5569):922-7. doi: 10.1126/science.1069398. Epub 2002 Apr 4. Science. 2002. PMID: 11934988 Free PMC article.
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. Fernandez-Capetillo O, et al. Among authors: chen j, chen ht. Nat Cell Biol. 2002 Dec;4(12):993-7. doi: 10.1038/ncb884. Nat Cell Biol. 2002. PMID: 12447390
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, Nussenzweig A. Difilippantonio S, et al. Among authors: chen ht. Nat Cell Biol. 2005 Jul;7(7):675-85. doi: 10.1038/ncb1270. Epub 2005 Jun 19. Nat Cell Biol. 2005. PMID: 15965469
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.
Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A. Santos MA, et al. Among authors: chen j, chen ht. J Exp Med. 2010 May 10;207(5):973-81. doi: 10.1084/jem.20092308. Epub 2010 Apr 12. J Exp Med. 2010. PMID: 20385748 Free PMC article.
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination.
Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A. Daniel JA, et al. Among authors: chen ht. Science. 2010 Aug 20;329(5994):917-23. doi: 10.1126/science.1187942. Epub 2010 Jul 29. Science. 2010. PMID: 20671152 Free PMC article.
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.
Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, Sedelnikova OA, Pilch DR, Rogakou EP, Celeste A, Chen HT, Nussenzweig A, Aladjem MI, Bonner WM, Pommier Y. Furuta T, et al. Among authors: chen ht. J Biol Chem. 2003 May 30;278(22):20303-12. doi: 10.1074/jbc.M300198200. Epub 2003 Mar 25. J Biol Chem. 2003. PMID: 12660252 Free article.
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX.
Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A. Chen HT, et al. Science. 2000 Dec 8;290(5498):1962-5. doi: 10.1126/science.290.5498.1962. Science. 2000. PMID: 11110662 Free PMC article.
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Ramiro AR, et al. Among authors: chen j, chen ht. Nature. 2006 Mar 2;440(7080):105-9. doi: 10.1038/nature04495. Epub 2006 Jan 8. Nature. 2006. PMID: 16400328 Free PMC article.
ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. Callén E, et al. Among authors: chen ht. Cell. 2007 Jul 13;130(1):63-75. doi: 10.1016/j.cell.2007.06.016. Epub 2007 Jun 28. Cell. 2007. PMID: 17599403 Free article.
923 results