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Drug-Drug Interaction Study to Assess the Effect of Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of the Novel Cereblon Modulator Avadomide (CC-122) in Healthy Adult Subjects.
Ogasawara K, MacGorman K, Liu L, Chen J, Carayannopoulos LN, Zhou S, Palmisano M, Li Y. Ogasawara K, et al. Among authors: chen j. J Clin Pharmacol. 2019 Dec;59(12):1620-1631. doi: 10.1002/jcph.1453. Epub 2019 Jun 6. J Clin Pharmacol. 2019. PMID: 31172535 Free PMC article.
Population Pharmacokinetics of CC-122.
Cheng Y, Chen J, Pourdehnad M, Zhou S, Li Y. Cheng Y, et al. Among authors: chen j. Clin Pharmacol. 2021 Apr 28;13:61-71. doi: 10.2147/CPAA.S310604. eCollection 2021. Clin Pharmacol. 2021. PMID: 33958900 Free PMC article.
Safety, Pharmacokinetics, and Pharmacodynamics of CC-90001 (BMS-986360), a c-Jun N-terminal Kinase Inhibitor, in Phase 1 Studies in Healthy Participants.
Ye Y, Gaudy A, Thomas M, Reyes J, Burkhardt B, Horan G, Liu L, Chen J, Ghosh A, Carayannopoulos LN, Tatosian DA, Palmisano M. Ye Y, et al. Among authors: chen j. Clin Pharmacol Drug Dev. 2022 Dec;11(12):1394-1404. doi: 10.1002/cpdd.1178. Epub 2022 Oct 18. Clin Pharmacol Drug Dev. 2022. PMID: 36256505 Free PMC article. Clinical Trial.
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