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Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer.
Guo ZQ, Zheng T, Chen B, Luo C, Ouyang S, Gong S, Li J, Mao LL, Lian F, Yang Y, Huang Y, Li L, Lu J, Zhang B, Zhou L, Ding H, Gao Z, Zhou L, Li G, Zhou R, Chen K, Liu J, Wen Y, Gong L, Ke Y, Yang SD, Qiu XB, Zhang N, Ren J, Zhong D, Yang CG, Liu J, Jiang H. Guo ZQ, et al. Among authors: chen k, chen b. Cancer Cell. 2016 Sep 12;30(3):474-484. doi: 10.1016/j.ccell.2016.08.003. Cancer Cell. 2016. PMID: 27622336 Free article.
SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer.
Li G, Ci W, Karmakar S, Chen K, Dhar R, Fan Z, Guo Z, Zhang J, Ke Y, Wang L, Zhuang M, Hu S, Li X, Zhou L, Li X, Calabrese MF, Watson ER, Prasad SM, Rinker-Schaeffer C, Eggener SE, Stricker T, Tian Y, Schulman BA, Liu J, White KP. Li G, et al. Among authors: chen k. Cancer Cell. 2014 Apr 14;25(4):455-68. doi: 10.1016/j.ccr.2014.02.007. Epub 2014 Mar 20. Cancer Cell. 2014. PMID: 24656772 Free PMC article.
Regulation of glucose metabolism by p62/SQSTM1 through HIF1α.
Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, Yu G, Xiao W, Xu H, Ye Z. Chen K, et al. J Cell Sci. 2016 Feb 15;129(4):817-30. doi: 10.1242/jcs.178756. Epub 2016 Jan 7. J Cell Sci. 2016. PMID: 26743088 Free PMC article.
Enhanced expression of caveolin-1 possesses diagnostic and prognostic value and promotes cell migration, invasion and sunitinib resistance in the clear cell renal cell carcinoma.
Ruan H, Li X, Yang H, Song Z, Tong J, Cao Q, Wang K, Xiao W, Xiao H, Chen X, Xu G, Bao L, Xiong Z, Yuan C, Liu L, Qu Y, Hu W, Gao Y, Ru Z, Chen K, Zhang X. Ruan H, et al. Among authors: chen k, chen x. Exp Cell Res. 2017 Sep 15;358(2):269-278. doi: 10.1016/j.yexcr.2017.07.004. Epub 2017 Jul 3. Exp Cell Res. 2017. PMID: 28684115
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