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NOX1/4 Inhibitor GKT-137831 Improves Erectile Function in Diabetic Rats by ROS Reduction and Endothelial Nitric Oxide Synthase Reconstitution.
Zhou B, Chen Y, Yuan H, Wang T, Feng J, Li M, Liu J. Zhou B, et al. Among authors: chen y. J Sex Med. 2021 Dec;18(12):1970-1983. doi: 10.1016/j.jsxm.2021.09.007. Epub 2021 Oct 11. J Sex Med. 2021. PMID: 34649814
CONCLUSION: GKT-137831 improves erectile function by 70% in type 1 DMED rats and constitutes a promising compound for the treatment of type 1 DMED, likely by inhibition of overactivated oxidative stress, down-regulation of proinflammatory factors, and amelioration of excessive au …
CONCLUSION: GKT-137831 improves erectile function by 70% in type 1 DMED rats and constitutes a promising compound for the treatment of type …
Correlations Among Genotype and Outcome in Chinese Male Patients With Congenital Hypogonadotropic Hypogonadism Under HCG Treatment.
Chen Y, Sun T, Niu Y, Wang D, Xiong Z, Li C, Liu K, Qiu Y, Sun Y, Gong J, Wang T, Wang S, Xu H, Liu J. Chen Y, et al. J Sex Med. 2020 Apr;17(4):645-657. doi: 10.1016/j.jsxm.2020.01.011. Epub 2020 Mar 12. J Sex Med. 2020. PMID: 32171629
CONCLUSION: Among all P/LP RSVs, P/LP PROKR2 RSVs might correlate with poor responses in CHH under hCG treatment; our study supports the pathogenicity assessment of American College of Medical Genetics and Genomics criteria in genetic counseling, to improve management of patients …
CONCLUSION: Among all P/LP RSVs, P/LP PROKR2 RSVs might correlate with poor responses in CHH under hCG treatment; our study supports the pat …
Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis.
Chen Y, Zhou B, Yu Z, Yuan P, Sun T, Gong J, Zhang Y, Wang T, Wang S, Liu K, Liu J. Chen Y, et al. J Sex Med. 2020 Aug;17(8):1434-1447. doi: 10.1016/j.jsxm.2020.04.390. Epub 2020 Jun 23. J Sex Med. 2020. PMID: 32586748
BE alleviated erectile dysfunction in rats with type I DMED probably by inhibiting 12-LOX expression, ameliorating endothelial nitric oxide synthase dysfunction, as well as suppressing oxidative stress and fibrosis. Chen Y, Zhou B, Yu Z, et al. Baicalein Alleviates …
BE alleviated erectile dysfunction in rats with type I DMED probably by inhibiting 12-LOX expression, ameliorating endothelial nitric oxide …
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