Cheng X - Search Results

1

The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.

Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer M, Dowling J, Xu L, Han R, Xu H. Cheng X, et al. Nat Med. 2014 Oct;20(10):1187-92. doi: 10.1038/nm.3611. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216637 Free PMC article.

2

A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.

Samie M, Wang X, Zhang X, Goschka A, Li X, Cheng X, Gregg E, Azar M, Zhuo Y, Garrity AG, Gao Q, Slaugenhaupt S, Pickel J, Zolov SN, Weisman LS, Lenk GM, Titus S, Bryant-Genevier M, Southall N, Juan M, Ferrer M, Xu H. Samie M, et al. Among authors: cheng x. Dev Cell. 2013 Sep 16;26(5):511-24. doi: 10.1016/j.devcel.2013.08.003. Epub 2013 Aug 29. Dev Cell. 2013. PMID: 23993788 Free PMC article.

3

Calcium signaling in membrane repair.

Cheng X, Zhang X, Yu L, Xu H. Cheng X, et al. Semin Cell Dev Biol. 2015 Sep;45:24-31. doi: 10.1016/j.semcdb.2015.10.031. Epub 2015 Oct 27. Semin Cell Dev Biol. 2015. PMID: 26519113 Free PMC article. Review.

4

A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.

Li X, Rydzewski N, Hider A, Zhang X, Yang J, Wang W, Gao Q, Cheng X, Xu H. Li X, et al. Among authors: cheng x. Nat Cell Biol. 2016 Apr;18(4):404-17. doi: 10.1038/ncb3324. Epub 2016 Mar 7. Nat Cell Biol. 2016. PMID: 26950892 Free PMC article.

5

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.

Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer M, Xu H. Zhang X, et al. Among authors: cheng x. Nat Commun. 2016 Jun 30;7:12109. doi: 10.1038/ncomms12109. Nat Commun. 2016. PMID: 27357649 Free PMC article.

6

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.

Dong XP, Cheng X, Mills E, Delling M, Wang F, Kurz T, Xu H. Dong XP, et al. Among authors: cheng x. Nature. 2008 Oct 16;455(7215):992-6. doi: 10.1038/nature07311. Epub 2008 Sep 14. Nature. 2008. PMID: 18794901 Free PMC article.

7

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.

Dong XP, Wang X, Shen D, Chen S, Liu M, Wang Y, Mills E, Cheng X, Delling M, Xu H. Dong XP, et al. Among authors: cheng x. J Biol Chem. 2009 Nov 13;284(46):32040-52. doi: 10.1074/jbc.M109.037184. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19638346 Free PMC article.

8

PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.

Dong XP, Shen D, Wang X, Dawson T, Li X, Zhang Q, Cheng X, Zhang Y, Weisman LS, Delling M, Xu H. Dong XP, et al. Among authors: cheng x. Nat Commun. 2010 Jul 13;1(4):38. doi: 10.1038/ncomms1037. Nat Commun. 2010. PMID: 20802798 Free PMC article.

9

A voltage-dependent K⁺ channel in the lysosome is required for refilling lysosomal Ca²⁺ stores.

Wang W, Zhang X, Gao Q, Lawas M, Yu L, Cheng X, Gu M, Sahoo N, Li X, Li P, Ireland S, Meredith A, Xu H. Wang W, et al. Among authors: cheng x. J Cell Biol. 2017 Jun 5;216(6):1715-1730. doi: 10.1083/jcb.201612123. Epub 2017 May 3. J Cell Biol. 2017. PMID: 28468834 Free PMC article.

10

Mucolipins: Intracellular TRPML1-3 channels.

Cheng X, Shen D, Samie M, Xu H. Cheng X, et al. FEBS Lett. 2010 May 17;584(10):2013-21. doi: 10.1016/j.febslet.2009.12.056. Epub 2010 Jan 13. FEBS Lett. 2010. PMID: 20074572 Free PMC article. Review.

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