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Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
Fujioka S, Schmidt C, Sclabas GM, Li Z, Pelicano H, Peng B, Yao A, Niu J, Zhang W, Evans DB, Abbruzzese JL, Huang P, Chiao PJ. Fujioka S, et al. Among authors: chiao pj. J Biol Chem. 2004 Jun 25;279(26):27549-59. doi: 10.1074/jbc.M313435200. Epub 2004 Apr 21. J Biol Chem. 2004. PMID: 15102862 Free article.
Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity.
Melisi D, Ossovskaya V, Zhu C, Rosa R, Ling J, Dougherty PM, Sherman BM, Abbruzzese JL, Chiao PJ. Melisi D, et al. Among authors: chiao pj. Clin Cancer Res. 2009 Oct 15;15(20):6367-77. doi: 10.1158/1078-0432.CCR-09-0910. Epub 2009 Oct 6. Clin Cancer Res. 2009. PMID: 19808866 Free PMC article.
Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter.
Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Peng B, et al. Among authors: chiao pj. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15193-8. doi: 10.1073/pnas.1005533107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696914 Free PMC article.
135 results