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Engineered proteins detect spontaneous DNA breakage in human and bacterial cells.
Shee C, Cox BD, Gu F, Luengas EM, Joshi MC, Chiu LY, Magnan D, Halliday JA, Frisch RL, Gibson JL, Nehring RB, Do HG, Hernandez M, Li L, Herman C, Hastings PJ, Bates D, Harris RS, Miller KM, Rosenberg SM. Shee C, et al. Among authors: chiu ly. Elife. 2013 Oct 29;2:e01222. doi: 10.7554/eLife.01222. Elife. 2013. PMID: 24171103 Free PMC article.
ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.
Leung JW, Makharashvili N, Agarwal P, Chiu LY, Pourpre R, Cammarata MB, Cannon JR, Sherker A, Durocher D, Brodbelt JS, Paull TT, Miller KM. Leung JW, et al. Among authors: chiu ly. Genes Dev. 2017 Feb 1;31(3):260-274. doi: 10.1101/gad.292516.116. Epub 2017 Feb 27. Genes Dev. 2017. PMID: 28242625 Free PMC article.
Bromodomain proteins: repairing DNA damage within chromatin.
Chiu LY, Gong F, Miller KM. Chiu LY, et al. Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731):20160286. doi: 10.1098/rstb.2016.0286. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28847823 Free PMC article. Review.
Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage.
Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM. Xia J, et al. Among authors: chiu ly. Cell. 2019 Jan 10;176(1-2):127-143.e24. doi: 10.1016/j.cell.2018.12.008. Cell. 2019. PMID: 30633903 Free PMC article.
Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses.
Lan Y, Yeung TL, Huang H, Wegener AA, Saha S, Toister-Achituv M, Jenkins MH, Chiu LY, Lazorchak A, Tarcic O, Wang H, Qi J, Locke G, Kalimi D, Qin G, Marelli B, Yu H, Gross AW, Derner MG, Soloviev M, Botte M, Sircar A, Ma H, Sood VD, Zhang D, Jiang F, Lo KM. Lan Y, et al. Among authors: chiu ly. J Immunother Cancer. 2022 Jul;10(7):e004122. doi: 10.1136/jitc-2021-004122. J Immunother Cancer. 2022. PMID: 35858707 Free PMC article.
108 results