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Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
Yoon MK, Kim BY, Lee JY, Ha JH, Kim SA, Lee DH, Lee MS, Lee MK, Choi JS, Cho JH, Kim JH, Kim S, Song J, Park SG, Park BC, Bae KH, Choi SU, Chi SW. Yoon MK, et al. Among authors: cho jh. J Biol Chem. 2018 Dec 21;293(51):19546-19558. doi: 10.1074/jbc.RA118.003061. Epub 2018 Nov 14. J Biol Chem. 2018. PMID: 30429221 Free PMC article.
Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model.
Takwale AD, Kim EY, Jang Y, Lee DH, Kim S, Choi Y, Kim JH, Lee DY, Kim Y, Lee SM, Lee HK, Nam HJ, Lee JY, Cho JH, Moon JH, Lee GS, Kim JH, Kim P, Park CH, Hwang JY. Takwale AD, et al. Among authors: cho jh. Bioorg Chem. 2022 Oct;127:105923. doi: 10.1016/j.bioorg.2022.105923. Epub 2022 Jun 13. Bioorg Chem. 2022. PMID: 35717803 Free article.
Discovery of pan-IAP degraders via a CRBN recruiting mechanism.
Park S, Kim D, Lee W, Cho JH, Kim S, Lee GS, Moon JH, Kim JA, Ha JD, Kim JH, Kim HJ. Park S, et al. Among authors: cho jh. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114910. doi: 10.1016/j.ejmech.2022.114910. Epub 2022 Nov 9. Eur J Med Chem. 2023. PMID: 36410083
4,104 results