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Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, Thornton JM, Gems D, Partridge L, Withers DJ. Selman C, et al. Among authors: choudhury ai. FASEB J. 2008 Mar;22(3):807-18. doi: 10.1096/fj.07-9261com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17928362
The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
Choudhury AI, Heffron H, Smith MA, Al-Qassab H, Xu AW, Selman C, Simmgen M, Clements M, Claret M, Maccoll G, Bedford DC, Hisadome K, Diakonov I, Moosajee V, Bell JD, Speakman JR, Batterham RL, Barsh GS, Ashford ML, Withers DJ. Choudhury AI, et al. J Clin Invest. 2005 Apr;115(4):940-50. doi: 10.1172/JCI24445. Epub 2005 Mar 24. J Clin Invest. 2005. PMID: 15841180 Free PMC article.
Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse.
Neganova I, Al-Qassab H, Heffron H, Selman C, Choudhury AI, Lingard SJ, Diakonov I, Patterson M, Ghatei M, Bloom SR, Franks S, Huhtaniemi I, Hardy K, Withers DJ. Neganova I, et al. Among authors: choudhury ai. Biol Reprod. 2007 Jun;76(6):1045-53. doi: 10.1095/biolreprod.106.059360. Epub 2007 Feb 28. Biol Reprod. 2007. PMID: 17329594
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ. Claret M, et al. Among authors: choudhury ai. J Clin Invest. 2007 Aug;117(8):2325-36. doi: 10.1172/JCI31516. J Clin Invest. 2007. PMID: 17671657 Free PMC article.
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, Thomas G, Carling D, Okkenhaug K, Thornton JM, Partridge L, Gems D, Withers DJ. Selman C, et al. Among authors: choudhury ai. Science. 2009 Oct 2;326(5949):140-4. doi: 10.1126/science.1177221. Science. 2009. PMID: 19797661 Free PMC article.
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, Selman C, Piipari K, Clements M, Lingard S, Chandarana K, Bell JD, Barsh GS, Smith AJ, Batterham RL, Ashford ML, Vanhaesebroeck B, Withers DJ. Al-Qassab H, et al. Among authors: choudhury ai. Cell Metab. 2009 Nov;10(5):343-54. doi: 10.1016/j.cmet.2009.09.008. Cell Metab. 2009. PMID: 19883613 Free PMC article.
Insulin receptor substrate 2 is a negative regulator of memory formation.
Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP. Irvine EE, et al. Among authors: choudhury ai. Learn Mem. 2011 May 19;18(6):375-83. doi: 10.1101/lm.2111311. Print 2011 Jun. Learn Mem. 2011. PMID: 21597043 Free PMC article.
33 results