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Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors.
Kehler J, Ritzen A, Langgård M, Petersen SL, Farah MM, Bundgaard C, Christoffersen CT, Nielsen J, Kilburn JP. Kehler J, et al. Among authors: christoffersen ct. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3738-42. doi: 10.1016/j.bmcl.2011.04.067. Epub 2011 Apr 30. Bioorg Med Chem Lett. 2011. PMID: 21602043
Synthesis and SAR study of a novel series of dopamine receptor agonists.
Risgaard R, Jensen M, Jørgensen M, Bang-Andersen B, Christoffersen CT, Jensen KG, Kristensen JL, Püschl A. Risgaard R, et al. Among authors: christoffersen ct. Bioorg Med Chem. 2014 Jan 1;22(1):381-92. doi: 10.1016/j.bmc.2013.11.012. Epub 2013 Nov 15. Bioorg Med Chem. 2014. PMID: 24296012
Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential.
Sams AG, Larsen K, Mikkelsen GK, Hentzer M, Christoffersen CT, Jensen KG, Frederiksen K, Bang-Andersen B. Sams AG, et al. Among authors: christoffersen ct. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5134-40. doi: 10.1016/j.bmcl.2012.05.048. Epub 2012 May 18. Bioorg Med Chem Lett. 2012. PMID: 22677319
Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain.
Kehler J, Kilburn JP, Estrada S, Christensen SR, Wall A, Thibblin A, Lubberink M, Bundgaard C, Brennum LT, Steiniger-Brach B, Christoffersen CT, Timmermann S, Kreilgaard M, Antoni G, Bang-Andersen B, Nielsen J. Kehler J, et al. Among authors: christoffersen ct. J Nucl Med. 2014 Sep;55(9):1513-8. doi: 10.2967/jnumed.114.140178. Epub 2014 Jul 3. J Nucl Med. 2014. PMID: 24994928 Free article.
41 results