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Altering the binding determinant on the interdigitating loop of mandelate racemase shifts specificity towards that of d-tartrate dehydratase.
Arch Biochem Biophys. 2022 Mar 30;718:109119. doi: 10.1016/j.abb.2022.109119. Epub 2022 Jan 8.
Arch Biochem Biophys. 2022.
PMID: 35016855
Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Brønsted base catalysts.
Fetter CM, Morrison ZA, Nagar M, Douglas CD, Bearne SL.
Fetter CM, et al.
Arch Biochem Biophys. 2019 May 15;666:116-126. doi: 10.1016/j.abb.2019.03.011. Epub 2019 Mar 29.
Arch Biochem Biophys. 2019.
PMID: 30935886
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Lower corticospinal excitability and greater fatigue among people with multiple sclerosis experiencing pain.
Murphy HM, Fetter CM, Snow NJ, Chaves AR, Downer MB, Ploughman M.
Murphy HM, et al. Among authors: fetter cm.
Mult Scler J Exp Transl Clin. 2023 Jan 5;9(1):20552173221143398. doi: 10.1177/20552173221143398. eCollection 2023 Jan-Mar.
Mult Scler J Exp Transl Clin. 2023.
PMID: 36636581
Free PMC article.
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Interrogating l-fuconate dehydratase with tartronate and 3-hydroxypyruvate reveals subtle differences within the mandelate racemase-subgroup of the enolase superfamily.
McGary LC, Fetter CM, Gu M, Hamilton MC, Kumar H, Kuehm OP, Douglas CD, Bearne SL.
McGary LC, et al. Among authors: fetter cm.
Arch Biochem Biophys. 2024 Apr;754:109924. doi: 10.1016/j.abb.2024.109924. Epub 2024 Feb 12.
Arch Biochem Biophys. 2024.
PMID: 38354877
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