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PTGES/PGE(2) signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model.
Wang T, Jing B, Xu D, Liao Y, Song H, Sun B, Guo W, Xu J, Li K, Hu M, Liu S, Ling J, Kuang Y, Zhang T, Zhang S, Yao F, Zhou BP, Deng J. Wang T, et al. Oncogene. 2020 Apr;39(15):3179-3194. doi: 10.1038/s41388-020-1207-6. Epub 2020 Feb 14. Oncogene. 2020. PMID: 32060421 Free PMC article.
Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. ...This suggests that the major role of PTGES/PGE(2) signaling in tumorigenicity and lung metastasis is through immunosuppression. Mechanistically, PTGES/PGE(2) signali …
Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. ...This suggests that the major rol …
Myeloid-derived suppressor cells impede T cell functionality and promote Th17 differentiation in oral squamous cell carcinoma.
Dar AA, Patil RS, Pradhan TN, Chaukar DA, D'Cruz AK, Chiplunkar SV. Dar AA, et al. Cancer Immunol Immunother. 2020 Jun;69(6):1071-1086. doi: 10.1007/s00262-020-02523-w. Epub 2020 Feb 26. Cancer Immunol Immunother. 2020. PMID: 32103293 Free PMC article.
Oral tumor microenvironment is characterized by chronic inflammation signified with infiltrating leukocytes and soluble mediators which cause immune suppression. However, how immunosuppressive cells like myeloid-derived suppressor …
Oral tumor microenvironment is characterized by chronic inflammation signified with infiltrating leukocyt …