Cilenti L - Search Results

1

THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.

Balakrishnan MP, Cilenti L, Mashak Z, Popat P, Alnemri ES, Zervos AS. Balakrishnan MP, et al. Among authors: cilenti l. Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H643-53. doi: 10.1152/ajpheart.00234.2009. Epub 2009 Jun 5. Am J Physiol Heart Circ Physiol. 2009. PMID: 19502560 Free PMC article.

2

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction.

Hegde R, Srinivasula SM, Zhang Z, Wassell R, Mukattash R, Cilenti L, DuBois G, Lazebnik Y, Zervos AS, Fernandes-Alnemri T, Alnemri ES. Hegde R, et al. Among authors: cilenti l. J Biol Chem. 2002 Jan 4;277(1):432-8. doi: 10.1074/jbc.M109721200. Epub 2001 Oct 17. J Biol Chem. 2002. PMID: 11606597 Free article.

3

Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

Cilenti L, Lee Y, Hess S, Srinivasula S, Park KM, Junqueira D, Davis H, Bonventre JV, Alnemri ES, Zervos AS. Cilenti L, et al. J Biol Chem. 2003 Mar 28;278(13):11489-94. doi: 10.1074/jbc.M212819200. Epub 2003 Jan 15. J Biol Chem. 2003. PMID: 12529364 Free article.

4

Random mutagenesis of PDZ(Omi) domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis.

Junqueira D, Cilenti L, Musumeci L, Sedivy JM, Zervos AS. Junqueira D, et al. Among authors: cilenti l. Oncogene. 2003 May 8;22(18):2772-81. doi: 10.1038/sj.onc.1206359. Oncogene. 2003. PMID: 12743600 Free article.

5

Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15.

Trencia A, Fiory F, Maitan MA, Vito P, Barbagallo AP, Perfetti A, Miele C, Ungaro P, Oriente F, Cilenti L, Zervos AS, Formisano P, Beguinot F. Trencia A, et al. Among authors: cilenti l. J Biol Chem. 2004 Nov 5;279(45):46566-72. doi: 10.1074/jbc.M406317200. Epub 2004 Aug 24. J Biol Chem. 2004. PMID: 15328349 Free article.

6

Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death.

Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS. Cilenti L, et al. J Biol Chem. 2004 Nov 26;279(48):50295-301. doi: 10.1074/jbc.M406006200. Epub 2004 Sep 15. J Biol Chem. 2004. PMID: 15371414 Free article.

7

Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.

Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Cilenti L, et al. Am J Physiol Renal Physiol. 2005 Feb;288(2):F371-9. doi: 10.1152/ajprenal.00154.2004. Epub 2004 Sep 28. Am J Physiol Renal Physiol. 2005. PMID: 15454391 Free article.

8

Acute renal failure in zebrafish: a novel system to study a complex disease.

Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Hentschel DM, et al. Among authors: cilenti l. Am J Physiol Renal Physiol. 2005 May;288(5):F923-9. doi: 10.1152/ajprenal.00386.2004. Epub 2004 Dec 29. Am J Physiol Renal Physiol. 2005. PMID: 15625083 Free article.

9

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.

Kotha A, Sekharam M, Cilenti L, Siddiquee K, Khaled A, Zervos AS, Carter B, Turkson J, Jove R. Kotha A, et al. Among authors: cilenti l. Mol Cancer Ther. 2006 Mar;5(3):621-9. doi: 10.1158/1535-7163.MCT-05-0268. Mol Cancer Ther. 2006. PMID: 16546976

10

The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion.

Althaus J, Siegelin MD, Dehghani F, Cilenti L, Zervos AS, Rami A. Althaus J, et al. Among authors: cilenti l. Neurochem Int. 2007 Jan;50(1):172-80. doi: 10.1016/j.neuint.2006.07.018. Epub 2006 Sep 15. Neurochem Int. 2007. PMID: 16978742

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