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Page 1
Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.
De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, Hipp MS, Houben B, Claes F, Charbonneau S, Delgado Blanco J, Plaisance S, Ramkissoon S, Ramkissoon L, Simons C, van den Brandt P, Weijenberg M, Van England M, Lambrechts S, Amant F, D'Hoore A, Ligon KL, Sagaert X, Schymkowitz J, Rousseau F. De Smet F, et al. Among authors: claes f. J Pathol. 2017 May;242(1):24-38. doi: 10.1002/path.4872. Epub 2017 Mar 23. J Pathol. 2017. PMID: 28035683
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V.
Claes F, Rudyak S, Laird AS, Louros N, Beerten J, Debulpaep M, Michiels E, van der Kant R, Van Durme J, De Baets G, Houben B, Ramakers M, Yuan K, Gwee SSL, Hernandez S, Broersen K, Oliveberg M, Moahamed B, Kirstein J, Robberecht W, Rousseau F, Schymkowitz J. Claes F, et al. Protein Eng Des Sel. 2019 Dec 31;32(10):443-457. doi: 10.1093/protein/gzaa008. Protein Eng Des Sel. 2019. PMID: 32399571
De novo design of a biologically active amyloid.
Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet P, Vande Velde G, Verfaillie C, Kaminski CF, De Strooper B, Hammarström P, Nilsson KP, Serpell L, Schymkowitz J, Rousseau F. Gallardo R, et al. Among authors: claes f. Science. 2016 Nov 11;354(6313):aah4949. doi: 10.1126/science.aah4949. Science. 2016. PMID: 27846578 Free article.
Role of neural guidance signals in blood vessel navigation.
Autiero M, De Smet F, Claes F, Carmeliet P. Autiero M, et al. Among authors: claes f. Cardiovasc Res. 2005 Feb 15;65(3):629-38. doi: 10.1016/j.cardiores.2004.09.013. Cardiovasc Res. 2005. PMID: 15664389 Review.
Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets.
Siemons M, Luyten K, Khodaparast L, Khodaparast L, Lecina J, Claes F, Gallardo R, Koole M, Ramakers M, Schymkowitz J, Bormans G, Rousseau F. Siemons M, et al. Among authors: claes f. Bioconjug Chem. 2021 Sep 15;32(9):2052-2064. doi: 10.1021/acs.bioconjchem.1c00369. Epub 2021 Sep 6. Bioconjug Chem. 2021. PMID: 34487434 Free PMC article.
Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis.
Khodaparast L, Khodaparast L, Gallardo R, Louros NN, Michiels E, Ramakrishnan R, Ramakers M, Claes F, Young L, Shahrooei M, Wilkinson H, Desager M, Mengistu Tadesse W, Nilsson KPR, Hammarström P, Aertsen A, Carpentier S, Van Eldere J, Rousseau F, Schymkowitz J. Khodaparast L, et al. Among authors: claes f. Nat Commun. 2018 Feb 28;9(1):866. doi: 10.1038/s41467-018-03131-0. Nat Commun. 2018. PMID: 29491361 Free PMC article.
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.
Geudens I, Herpers R, Hermans K, Segura I, Ruiz de Almodovar C, Bussmann J, De Smet F, Vandevelde W, Hogan BM, Siekmann A, Claes F, Moore JC, Pistocchi AS, Loges S, Mazzone M, Mariggi G, Bruyère F, Cotelli F, Kerjaschki D, Noël A, Foidart JM, Gerhardt H, Ny A, Langenberg T, Lawson ND, Duckers HJ, Schulte-Merker S, Carmeliet P, Dewerchin M. Geudens I, et al. Among authors: claes f. Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1695-702. doi: 10.1161/ATVBAHA.110.203034. Epub 2010 May 13. Arterioscler Thromb Vasc Biol. 2010. PMID: 20466977 Free PMC article.
Role of synectin in lymphatic development in zebrafish and frogs.
Hermans K, Claes F, Vandevelde W, Zheng W, Geudens I, Orsenigo F, De Smet F, Gjini E, Anthonis K, Ren B, Kerjaschki D, Autiero M, Ny A, Simons M, Dewerchin M, Schulte-Merker S, Dejana E, Alitalo K, Carmeliet P. Hermans K, et al. Among authors: claes f. Blood. 2010 Oct 28;116(17):3356-66. doi: 10.1182/blood-2009-11-254557. Epub 2010 Jul 14. Blood. 2010. PMID: 20631376 Free PMC article.
FAF1, a gene that is disrupted in cleft palate and has conserved function in zebrafish.
Ghassibe-Sabbagh M, Desmyter L, Langenberg T, Claes F, Boute O, Bayet B, Pellerin P, Hermans K, Backx L, Mansilla MA, Imoehl S, Nowak S, Ludwig KU, Baluardo C, Ferrian M, Mossey PA, Noethen M, Dewerchin M, François G, Revencu N, Vanwijck R, Hecht J, Mangold E, Murray J, Rubini M, Vermeesch JR, Poirel HA, Carmeliet P, Vikkula M. Ghassibe-Sabbagh M, et al. Among authors: claes f. Am J Hum Genet. 2011 Feb 11;88(2):150-61. doi: 10.1016/j.ajhg.2011.01.003. Epub 2011 Feb 3. Am J Hum Genet. 2011. PMID: 21295280 Free PMC article.
107 results