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Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
White MA, Lin Z, Kim E, Henstridge CM, Pena Altamira E, Hunt CK, Burchill E, Callaghan I, Loreto A, Brown-Wright H, Mead R, Simmons C, Cash D, Coleman MP, Sreedharan J. White MA, et al. Among authors: coleman mp. Acta Neuropathol Commun. 2019 Oct 28;7(1):166. doi: 10.1186/s40478-019-0800-9. Acta Neuropathol Commun. 2019. PMID: 31661035 Free PMC article.
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
White MA, Kim E, Duffy A, Adalbert R, Phillips BU, Peters OM, Stephenson J, Yang S, Massenzio F, Lin Z, Andrews S, Segonds-Pichon A, Metterville J, Saksida LM, Mead R, Ribchester RR, Barhomi Y, Serre T, Coleman MP, Fallon JR, Bussey TJ, Brown RH Jr, Sreedharan J. White MA, et al. Among authors: coleman mp. Nat Neurosci. 2018 Apr;21(4):552-563. doi: 10.1038/s41593-018-0113-5. Epub 2018 Mar 19. Nat Neurosci. 2018. PMID: 29556029 Free PMC article.
Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
White MA, Kim E, Duffy A, Adalbert R, Phillips BU, Peters OM, Stephenson J, Yang S, Massenzio F, Lin Z, Andrews S, Segonds-Pichon A, Metterville J, Saksida LM, Mead R, Ribchester RR, Barhomi Y, Serre T, Coleman MP, Fallon JR, Bussey TJ, Brown RH Jr, Sreedharan J. White MA, et al. Among authors: coleman mp. Nat Neurosci. 2018 Aug;21(8):1138. doi: 10.1038/s41593-018-0160-y. Nat Neurosci. 2018. PMID: 29872124
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.
Loreto A, Hill CS, Hewitt VL, Orsomando G, Angeletti C, Gilley J, Lucci C, Sanchez-Martinez A, Whitworth AJ, Conforti L, Dajas-Bailador F, Coleman MP. Loreto A, et al. Among authors: coleman mp. Neurobiol Dis. 2020 Feb;134:104678. doi: 10.1016/j.nbd.2019.104678. Epub 2019 Nov 15. Neurobiol Dis. 2020. PMID: 31740269 Free PMC article.
411 results