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Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance.
Margiotta N, Natile G, Capitelli F, Fanizzi FP, Boccarelli A, De Rinaldis P, Giordano D, Coluccia M. Margiotta N, et al. Among authors: coluccia m. J Inorg Biochem. 2006 Nov;100(11):1849-57. doi: 10.1016/j.jinorgbio.2006.07.010. Epub 2006 Aug 3. J Inorg Biochem. 2006. PMID: 16959321
Antitumor active trans-platinum compounds.
Natile G, Coluccia M. Natile G, et al. Among authors: coluccia m. Met Ions Biol Syst. 2004;42:209-50. Met Ions Biol Syst. 2004. PMID: 15206104 Review. No abstract available.
Trans-platinum complexes in cancer therapy.
Coluccia M, Natile G. Coluccia M, et al. Anticancer Agents Med Chem. 2007 Jan;7(1):111-23. doi: 10.2174/187152007779314080. Anticancer Agents Med Chem. 2007. PMID: 17266508 Review.
Platinum complexes can inhibit matrix metalloproteinase activity: platinum-diethyl[(methylsulfinyl)methyl]phosphonate complexes as inhibitors of matrix metalloproteinases 2, 3, 9, and 12.
Sasanelli R, Boccarelli A, Giordano D, Laforgia M, Arnesano F, Natile G, Cardellicchio C, Capozzi MA, Coluccia M. Sasanelli R, et al. Among authors: coluccia m. J Med Chem. 2007 Jul 26;50(15):3434-41. doi: 10.1021/jm061435l. Epub 2007 Jun 21. J Med Chem. 2007. PMID: 17583333
59 results