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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1877 1
1880 53
1881 97
1882 118
1883 112
1884 103
1885 85
1886 44
1887 74
1888 45
1889 41
1890 163
1891 167
1892 175
1893 97
1894 126
1895 340
1896 417
1897 382
1898 287
1899 246
1900 262
1901 254
1902 195
1903 81
1920 1
1934 1
1936 1
1937 35
1938 126
1939 122
1940 109
1941 111
1942 87
1943 92
1944 83
1945 161
1946 286
1947 281
1948 304
1949 339
1950 287
1951 356
1952 361
1953 359
1954 390
1955 357
1956 385
1957 407
1958 421
1959 438
1960 354
1961 495
1962 618
1963 563
1964 704
1965 680
1966 686
1967 769
1968 972
1969 1031
1970 921
1971 1062
1972 1127
1973 1291
1974 1196
1975 1494
1976 1280
1977 1020
1978 1140
1979 1110
1980 945
1981 1065
1982 1459
1983 1499
1984 1630
1985 1841
1986 1684
1987 1820
1988 1699
1989 1598
1990 1545
1991 1802
1992 1774
1993 1531
1994 1347
1995 1375
1996 1382
1997 1483
1998 1517
1999 1484
2000 2272
2001 2341
2002 2531
2003 2749
2004 2749
2005 2912
2006 3244
2007 3403
2008 3201
2009 3102
2010 3190
2011 3160
2012 3150
2013 3203
2014 3100
2015 3135
2016 3432
2017 3525
2018 3391
2019 3419
2020 3447
2021 3518
2022 2901
2023 2709
2024 1309

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121,125 results

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Page 1
COMP-Related Pseudoachondroplasia.
Briggs MD, Wright MJ. Briggs MD, et al. 2004 Aug 20 [updated 2023 Nov 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2004 Aug 20 [updated 2023 Nov 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301660 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: COMP-related pseudoachondroplasia (COMP-PSACH) is characterized by normal length at birth and normal facies. ...Each child of an individual with COMP-PSACH and a reproductive partner with normal bone growth has a 50% chance of inheri …
CLINICAL CHARACTERISTICS: COMP-related pseudoachondroplasia (COMP-PSACH) is characterized by normal length at birth and normal …
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF-beta Signaling Pathway.
Cai X, Li M, Zhong Y, Yang W, Liang Z. Cai X, et al. Cardiovasc Toxicol. 2023 Oct;23(9-10):305-316. doi: 10.1007/s12012-023-09799-1. Epub 2023 Aug 16. Cardiovasc Toxicol. 2023. PMID: 37584842
Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-beta as well as their role in AF remains undefined. ...The involvement of TGF-beta pathway was further discussed. The expression of COMP was the most si …
Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-beta as well as the …
Role of TSP-5/COMP in pseudoachondroplasia.
Posey KL, Hayes E, Haynes R, Hecht JT. Posey KL, et al. Int J Biochem Cell Biol. 2004 Jun;36(6):1005-12. doi: 10.1016/j.biocel.2004.01.011. Int J Biochem Cell Biol. 2004. PMID: 15094116 Review.
Functional studies have shown that COMP binds types II and IX collagens but the role of COMP in the extracellular matrix remains to be defined. Mutations in COMP interfere with calcium-binding and protein conformation. PSACH growth plate and growth plate chon …
Functional studies have shown that COMP binds types II and IX collagens but the role of COMP in the extracellular matrix remai …
COMP promotes pancreatic fibrosis by activating pancreatic stellate cells through CD36-ERK/AKT signaling pathways.
Wang Y, Li HT, Liu G, Jiang CS, Ni YH, Zeng JH, Lin X, Wang QY, Li DZ, Wang W, Zeng XP. Wang Y, et al. Cell Signal. 2024 Jun;118:111135. doi: 10.1016/j.cellsig.2024.111135. Epub 2024 Mar 11. Cell Signal. 2024. PMID: 38479555
TGF-beta1 stimulates the activation of HPSCs and increases the expression of COMP. Knockdown of COMP inhibited proliferation and migration of HPSCs. ...Interfering with the expression of COMP or the communication between COMP and CD36 on PSCs may be th …
TGF-beta1 stimulates the activation of HPSCs and increases the expression of COMP. Knockdown of COMP inhibited proliferation a …
COMP: A Potential Early Biomarker of RAS After Lung Transplantation.
Novo M, Westin J, Andersson LM, Jonsson Berdenius A, Nordén R, Magnusson JM. Novo M, et al. Transplant Direct. 2021 Jul 19;7(8):e730. doi: 10.1097/TXD.0000000000001189. eCollection 2021 Aug. Transplant Direct. 2021. PMID: 34291152 Free PMC article.
CLAD's pathogenesis is largely unknown, but previous findings suggest that it is associated with increased fibrosis in the transplanted lung. Cartilage oligomeric matrix protein (COMP) has been associated with multiple fibrotic conditions. The current study aimed to explor …
CLAD's pathogenesis is largely unknown, but previous findings suggest that it is associated with increased fibrosis in the transplanted lung …
COMP-assisted collagen secretion--a novel intracellular function required for fibrosis.
Schulz JN, Nüchel J, Niehoff A, Bloch W, Schönborn K, Hayashi S, Kamper M, Brinckmann J, Plomann M, Paulsson M, Krieg T, Zaucke F, Eckes B. Schulz JN, et al. J Cell Sci. 2016 Feb 15;129(4):706-16. doi: 10.1242/jcs.180216. Epub 2016 Jan 8. J Cell Sci. 2016. PMID: 26746240
Surprisingly, COMP also fulfills an important intracellular function in assisting efficient secretion of collagens, which were retained in the endoplasmic reticulum of COMP-null fibroblasts. Accordingly, COMP-null mice showed severely attenuated fibrotic resp …
Surprisingly, COMP also fulfills an important intracellular function in assisting efficient secretion of collagens, which were retain …
COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis.
Maly K, Andres Sastre E, Farrell E, Meurer A, Zaucke F. Maly K, et al. Int J Mol Sci. 2021 Feb 24;22(5):2242. doi: 10.3390/ijms22052242. Int J Mol Sci. 2021. PMID: 33668140 Free PMC article.
Our results demonstrate that COMP could attract chondrocytes and may contribute to a repopulation of damaged cartilage areas, while TSP-4 did not affect this process. In contrast, both proteins similarly promoted the synthesis and matrix formation of collagen II, IX, XII a …
Our results demonstrate that COMP could attract chondrocytes and may contribute to a repopulation of damaged cartilage areas, while T …
Outcomes of Transfusion With Whole Blood, Component Therapy, or Both in Adult Civilian Trauma Patients: A Systematic Review and Meta-Analysis.
Ngatuvai M, Zagales I, Sauder M, Andrade R, Santos RG, Bilski T, Kornblith L, Elkbuli A. Ngatuvai M, et al. J Surg Res. 2023 Jul;287:193-201. doi: 10.1016/j.jss.2023.02.010. Epub 2023 Mar 20. J Surg Res. 2023. PMID: 36947979 Review.
INTRODUCTION: This systematic review and meta-analysis was conducted to compare outcomes, including transfusion volume, complications, intensive care unit length of stay, and mortality for adult civilian trauma patients transfused with whole blood (WB), components (COMP), …
INTRODUCTION: This systematic review and meta-analysis was conducted to compare outcomes, including transfusion volume, complications, inten …
COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.
Jia Y, Wang M, Mao C, Yu F, Wang Y, Xiao R, Jiang C, Zheng L, Xu Q, Zheng M, Fu Y, Hu Q, Kong W. Jia Y, et al. Cell Death Dis. 2018 Jun 4;9(6):676. doi: 10.1038/s41419-018-0703-x. Cell Death Dis. 2018. PMID: 29867124 Free PMC article.
Moreover, microarray analysis revealed that COMP deficiency impaired mitochondrial oxidative phosphorylation in VSMCs. ...Moreover, the interactome of mitochondrial COMP revealed that COMP interacted with prohibitin 2, and COMP-prohibitin 2 interaction …
Moreover, microarray analysis revealed that COMP deficiency impaired mitochondrial oxidative phosphorylation in VSMCs. ...Moreover, t …
Cartilage oligomeric matrix protein (COMP) promotes cell proliferation in early-onset colon cancer tumorigenesis.
Nfonsam VN, Jecius HC, Janda J, Omesiete PN, Elquza E, Scott AJ, Nfonsam LE, Jandova J. Nfonsam VN, et al. Surg Endosc. 2020 Sep;34(9):3992-3998. doi: 10.1007/s00464-019-07185-z. Epub 2019 Oct 15. Surg Endosc. 2020. PMID: 31617091
HT-29 (low COMP expression) and CaCo-2 (high COMP expression) cells were used for in vitro proliferation studies. ...Staining for COMP and Ki67 revealed high COMP protein levels in EOCC compared to LOCC patients. ...
HT-29 (low COMP expression) and CaCo-2 (high COMP expression) cells were used for in vitro proliferation studies. ...Staining …
121,125 results
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