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Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Watts JC, et al. Among authors: condello c. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10323-8. doi: 10.1073/pnas.1408900111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982139 Free PMC article.
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. Giles K, et al. Among authors: condello c. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12. doi: 10.1124/jpet.115.224659. Epub 2015 Jul 29. J Pharmacol Exp Ther. 2015. PMID: 26224882 Free PMC article.
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Giles K, et al. Among authors: condello c. J Pharmacol Exp Ther. 2016 Sep;358(3):537-47. doi: 10.1124/jpet.116.235556. Epub 2016 Jun 17. J Pharmacol Exp Ther. 2016. PMID: 27317802 Free PMC article.
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. Stöhr J, et al. Among authors: condello c. Nat Chem. 2017 Sep;9(9):874-881. doi: 10.1038/nchem.2754. Epub 2017 Apr 3. Nat Chem. 2017. PMID: 28837163 Free PMC article.
A novel vector for transgenesis in the rat CNS.
Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. Lopez TP, et al. Among authors: condello c. Acta Neuropathol Commun. 2017 Nov 21;5(1):84. doi: 10.1186/s40478-017-0484-y. Acta Neuropathol Commun. 2017. PMID: 29157304 Free PMC article.
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. Condello C, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E782-E791. doi: 10.1073/pnas.1714966115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311311 Free PMC article.
Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain.
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB. Aoyagi A, et al. Among authors: condello c. Sci Transl Med. 2019 May 1;11(490):eaat8462. doi: 10.1126/scitranslmed.aat8462. Sci Transl Med. 2019. PMID: 31043574 Free PMC article.
62 results