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SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC. Perez-Bermejo JA, et al. Among authors: conklin br. Sci Transl Med. 2021 Apr 21;13(590):eabf7872. doi: 10.1126/scitranslmed.abf7872. Epub 2021 Mar 15. Sci Transl Med. 2021. PMID: 33723017 Free PMC article.
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
Judge LM, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. Judge LM, et al. Among authors: conklin br. JCI Insight. 2017 Jul 20;2(14):e94623. doi: 10.1172/jci.insight.94623. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724793 Free PMC article.
Automated Design of Pluripotent Stem Cell Self-Organization.
Libby ARG, Briers D, Haghighi I, Joy DA, Conklin BR, Belta C, McDevitt TC. Libby ARG, et al. Among authors: conklin br. Cell Syst. 2019 Nov 27;9(5):483-495.e10. doi: 10.1016/j.cels.2019.10.008. Epub 2019 Nov 20. Cell Syst. 2019. PMID: 31759947 Free PMC article.
SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients.
Pérez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Ramadoss GN, Silva AC, Flanigan WR, Li H, Nakamura K, Whitman JD, Ott M, Conklin BR, McDevitt TC. Pérez-Bermejo JA, et al. Among authors: conklin br. bioRxiv [Preprint]. 2020 Sep 12:2020.08.25.265561. doi: 10.1101/2020.08.25.265561. bioRxiv. 2020. PMID: 32935097 Free PMC article. Updated. Preprint.
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Samelson AJ, Tran QD, Robinot R, Carrau L, Rezelj VV, Mac Kain A, Chen M, Ramadoss GN, Guo X, Lim SA, Lui I, Nunez J, Rockwood SJ, Wang J, Liu N, Carlson-Stevermer J, Oki J, Maures T, Holden K, Weissman JS, Wells JA, Conklin BR, TenOever BR, Chakrabarti LA, Vignuzzi M, Tian R, Kampmann M. Samelson AJ, et al. Among authors: conklin br. bioRxiv [Preprint]. 2021 Sep 20:2021.01.19.427194. doi: 10.1101/2021.01.19.427194. bioRxiv. 2021. PMID: 33501440 Free PMC article. Updated. Preprint.
Bioengineered optogenetic model of human neuromuscular junction.
Vila OF, Chavez M, Ma SP, Yeager K, Zholudeva LV, Colón-Mercado JM, Qu Y, Nash TR, Lai C, Feliciano CM, Carter M, Kamm RD, Judge LM, Conklin BR, Ward ME, McDevitt TC, Vunjak-Novakovic G. Vila OF, et al. Among authors: conklin br. Biomaterials. 2021 Sep;276:121033. doi: 10.1016/j.biomaterials.2021.121033. Epub 2021 Jul 30. Biomaterials. 2021. PMID: 34403849 Free PMC article.
153 results