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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Rådmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Förster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M. Friedmann Angeli JP, et al. Among authors: conrad m. Nat Cell Biol. 2014 Dec;16(12):1180-91. doi: 10.1038/ncb3064. Epub 2014 Nov 17. Nat Cell Biol. 2014. PMID: 25402683 Free PMC article.
Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation.
Kagan VE, Tyurina YY, Tyurin VA, Mohammadyani D, Angeli JP, Baranov SV, Klein-Seetharaman J, Friedlander RM, Mallampalli RK, Conrad M, Bayir H. Kagan VE, et al. Among authors: conrad m. Antioxid Redox Signal. 2015 Jun 20;22(18):1667-80. doi: 10.1089/ars.2014.6219. Epub 2015 Mar 31. Antioxid Redox Signal. 2015. PMID: 25566681 Free PMC article. Review.
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H. Kagan VE, et al. Among authors: conrad m. Nat Chem Biol. 2017 Jan;13(1):81-90. doi: 10.1038/nchembio.2238. Epub 2016 Nov 14. Nat Chem Biol. 2017. PMID: 27842066 Free PMC article.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. Doll S, et al. Among authors: conrad m. Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14. Nat Chem Biol. 2017. PMID: 27842070 Free PMC article.
Iron and ferroptosis: A still ill-defined liaison.
Doll S, Conrad M. Doll S, et al. Among authors: conrad m. IUBMB Life. 2017 Jun;69(6):423-434. doi: 10.1002/iub.1616. Epub 2017 Mar 9. IUBMB Life. 2017. PMID: 28276141 Free article. Review.
Ferroptosis Inhibition: Mechanisms and Opportunities.
Angeli JPF, Shah R, Pratt DA, Conrad M. Angeli JPF, et al. Among authors: conrad m. Trends Pharmacol Sci. 2017 May;38(5):489-498. doi: 10.1016/j.tips.2017.02.005. Epub 2017 Mar 28. Trends Pharmacol Sci. 2017. PMID: 28363764 Review.
1,306 results