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Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.
Xiao Z, Song S, Chen D, van Merkerk R, van der Wouden PE, Cool RH, Quax WJ, Poelarends GJ, Melgert BN, Dekker FJ. Xiao Z, et al. Among authors: cool rh. Angew Chem Int Ed Engl. 2021 Aug 2;60(32):17514-17521. doi: 10.1002/anie.202101864. Epub 2021 Jun 26. Angew Chem Int Ed Engl. 2021. PMID: 34018657 Free PMC article.
7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor.
Xiao Z, Chen D, Song S, van der Vlag R, van der Wouden PE, van Merkerk R, Cool RH, Hirsch AKH, Melgert BN, Quax WJ, Poelarends GJ, Dekker FJ. Xiao Z, et al. Among authors: cool rh. J Med Chem. 2020 Oct 22;63(20):11920-11933. doi: 10.1021/acs.jmedchem.0c01160. Epub 2020 Oct 13. J Med Chem. 2020. PMID: 32940040 Free PMC article.
Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells.
Xiao Z, Osipyan A, Song S, Chen D, Schut RA, van Merkerk R, van der Wouden PE, Cool RH, Quax WJ, Melgert BN, Poelarends GJ, Dekker FJ. Xiao Z, et al. Among authors: cool rh. J Med Chem. 2022 Feb 10;65(3):2059-2077. doi: 10.1021/acs.jmedchem.1c01598. Epub 2022 Jan 18. J Med Chem. 2022. PMID: 35041425 Free PMC article.
Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.
Kok T, Wapenaar H, Wang K, Neochoritis CG, Zarganes-Tzitzikas T, Proietti G, Eleftheriadis N, Kurpiewska K, Kalinowska-Tłuścik J, Cool RH, Poelarends GJ, Dömling A, Dekker FJ. Kok T, et al. Among authors: cool rh. Bioorg Med Chem. 2018 Mar 1;26(5):999-1005. doi: 10.1016/j.bmc.2017.12.032. Epub 2017 Dec 24. Bioorg Med Chem. 2018. PMID: 29428527 Free PMC article.
82 results