Coombs GH - Search Results

1

Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.

Basselin M, Denise H, Coombs GH, Barrett MP. Basselin M, et al. Among authors: coombs gh. Antimicrob Agents Chemother. 2002 Dec;46(12):3731-8. doi: 10.1128/AAC.46.12.3731-3738.2002. Antimicrob Agents Chemother. 2002. PMID: 12435669 Free PMC article.

2

Putrescine and spermidine transport in Leishmania.

Basselin M, Coombs GH, Barrett MP. Basselin M, et al. Among authors: coombs gh. Mol Biochem Parasitol. 2000 Jun;109(1):37-46. doi: 10.1016/s0166-6851(00)00234-6. Mol Biochem Parasitol. 2000. PMID: 10924755

3

Expression of multiple CPB genes encoding cysteine proteases is required for Leishmania mexicana virulence in vivo.

Denise H, McNeil K, Brooks DR, Alexander J, Coombs GH, Mottram JC. Denise H, et al. Among authors: coombs gh. Infect Immun. 2003 Jun;71(6):3190-5. doi: 10.1128/IAI.71.6.3190-3195.2003. Infect Immun. 2003. PMID: 12761098 Free PMC article.

4

Recent advances in identifying and validating drug targets in trypanosomes and leishmanias.

Barrett MP, Mottram JC, Coombs GH. Barrett MP, et al. Among authors: coombs gh. Trends Microbiol. 1999 Feb;7(2):82-8. doi: 10.1016/s0966-842x(98)01433-4. Trends Microbiol. 1999. PMID: 10081086 Review.

5

The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element.

Brooks DR, Denise H, Westrop GD, Coombs GH, Mottram JC. Brooks DR, et al. Among authors: coombs gh. J Biol Chem. 2001 Dec 14;276(50):47061-9. doi: 10.1074/jbc.M108498200. Epub 2001 Oct 9. J Biol Chem. 2001. PMID: 11592967 Free article.

6

Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5.

Denise H, Poot J, Jiménez M, Ambit A, Herrmann DC, Vermeulen AN, Coombs GH, Mottram JC. Denise H, et al. Among authors: coombs gh. BMC Mol Biol. 2006 Nov 13;7:42. doi: 10.1186/1471-2199-7-42. BMC Mol Biol. 2006. PMID: 17101050 Free PMC article.

7

Generation of Leishmania mutants lacking antibiotic resistance genes using a versatile hit-and-run targeting strategy.

Denise H, Coombs GH, Mottram JC. Denise H, et al. Among authors: coombs gh. FEMS Microbiol Lett. 2004 Jun 1;235(1):89-94. doi: 10.1016/j.femsle.2004.04.015. FEMS Microbiol Lett. 2004. PMID: 15158266

8

Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose.

Lamour N, Rivière L, Coustou V, Coombs GH, Barrett MP, Bringaud F. Lamour N, et al. Among authors: coombs gh. J Biol Chem. 2005 Mar 25;280(12):11902-10. doi: 10.1074/jbc.M414274200. Epub 2005 Jan 21. J Biol Chem. 2005. PMID: 15665328 Free article.

9

Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity.

Buxbaum LU, Denise H, Coombs GH, Alexander J, Mottram JC, Scott P. Buxbaum LU, et al. Among authors: coombs gh. J Immunol. 2003 Oct 1;171(7):3711-7. doi: 10.4049/jimmunol.171.7.3711. J Immunol. 2003. PMID: 14500670

10

Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes.

Biddau M, Santha Kumar TR, Henrich P, Laine LM, Blackburn GJ, Chokkathukalam A, Li T, Lee Sim K, King L, Hoffman SL, Barrett MP, Coombs GH, McFadden GI, Fidock DA, Müller S, Sheiner L. Biddau M, et al. Among authors: coombs gh. Int J Parasitol. 2021 May;51(6):441-453. doi: 10.1016/j.ijpara.2020.10.011. Epub 2021 Mar 11. Int J Parasitol. 2021. PMID: 33713652 Free PMC article.

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