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Nox1-derived oxidative stress as a common pathogenic link between obesity and hyperoxaluria-related kidney injury.
Sáenz-Medina J, Muñoz M, Sanchez A, Rodriguez C, Jorge E, Corbacho C, Izquierdo D, Santos M, Donoso E, Virumbrales E, Sanchez A, Ramil E, Coronado MJ, Prieto D, Carballido J. Sáenz-Medina J, et al. Among authors: corbacho c. Urolithiasis. 2020 Dec;48(6):481-492. doi: 10.1007/s00240-019-01170-w. Epub 2019 Nov 5. Urolithiasis. 2020. PMID: 31690958
Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries.
Muñoz M, Martínez MP, López-Oliva ME, Rodríguez C, Corbacho C, Carballido J, García-Sacristán A, Hernández M, Rivera L, Sáenz-Medina J, Prieto D. Muñoz M, et al. Among authors: corbacho c. Redox Biol. 2018 Oct;19:92-104. doi: 10.1016/j.redox.2018.08.004. Epub 2018 Aug 7. Redox Biol. 2018. PMID: 30125808 Free PMC article.
Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation.
Rodríguez C, Contreras C, Sáenz-Medina J, Muñoz M, Corbacho C, Carballido J, García-Sacristán A, Hernandez M, López M, Rivera L, Prieto D. Rodríguez C, et al. Among authors: corbacho c. Redox Biol. 2020 Jul;34:101575. doi: 10.1016/j.redox.2020.101575. Epub 2020 May 16. Redox Biol. 2020. PMID: 32470915 Free PMC article.
35 results