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All Paths Lead to TRIM25.
Zhou H, Costello JC. Zhou H, et al. Among authors: costello jc. Trends Cancer. 2017 Oct;3(10):673-675. doi: 10.1016/j.trecan.2017.08.005. Trends Cancer. 2017. PMID: 28958384
Next-Generation Machine Learning for Biological Networks.
Camacho DM, Collins KM, Powers RK, Costello JC, Collins JJ. Camacho DM, et al. Among authors: costello jc. Cell. 2018 Jun 14;173(7):1581-1592. doi: 10.1016/j.cell.2018.05.015. Epub 2018 Jun 7. Cell. 2018. PMID: 29887378 Free article. Review.
Metastatic cells are preferentially vulnerable to lysosomal inhibition.
Morgan MJ, Fitzwalter BE, Owens CR, Powers RK, Sottnik JL, Gamez G, Costello JC, Theodorescu D, Thorburn A. Morgan MJ, et al. Among authors: costello jc. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8479-E8488. doi: 10.1073/pnas.1706526115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127018 Free PMC article.
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Powers RK, et al. Among authors: costello jc. Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9. Nat Commun. 2019. PMID: 31628327 Free PMC article.
Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
Zhou H, Blevins MA, Hsu JY, Kong D, Galbraith MD, Goodspeed A, Culp-Hill R, Oliphant MUJ, Ramirez D, Zhang L, Trinidad-Pineiro J, Mathews Griner L, King R, Barnaeva E, Hu X, Southall NT, Ferrer M, Gustafson DL, Regan DP, D'Alessandro A, Costello JC, Patnaik S, Marugan J, Zhao R, Ford HL. Zhou H, et al. Among authors: costello jc. Cancer Res. 2020 Jun 15;80(12):2689-2702. doi: 10.1158/0008-5472.CAN-20-0435. Epub 2020 Apr 27. Cancer Res. 2020. PMID: 32341035 Free PMC article.
The Capacity of the Ovarian Cancer Tumor Microenvironment to Integrate Inflammation Signaling Conveys a Shorter Disease-free Interval.
Jordan KR, Sikora MJ, Slansky JE, Minic A, Richer JK, Moroney MR, Hu J, Wolsky RJ, Watson ZL, Yamamoto TM, Costello JC, Clauset A, Behbakht K, Kumar TR, Bitler BG. Jordan KR, et al. Among authors: costello jc. Clin Cancer Res. 2020 Dec 1;26(23):6362-6373. doi: 10.1158/1078-0432.CCR-20-1762. Epub 2020 Sep 14. Clin Cancer Res. 2020. PMID: 32928797 Free PMC article.
86 results