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A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition.
Hum Mol Genet. 2006 Dec 15;15(24):3544-58. doi: 10.1093/hmg/ddl431. Epub 2006 Nov 13.
Hum Mol Genet. 2006.
PMID: 17101632
Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.
Fassier C, Tarrade A, Peris L, Courageot S, Mailly P, Dalard C, Delga S, Roblot N, Lefèvre J, Job D, Hazan J, Curmi PA, Melki J.
Fassier C, et al. Among authors: courageot s.
Dis Model Mech. 2013 Jan;6(1):72-83. doi: 10.1242/dmm.008946. Epub 2012 Jul 5.
Dis Model Mech. 2013.
PMID: 22773755
Free PMC article.
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Deletion of murine Smn exon 7 directed to liver leads to severe defect of liver development associated with iron overload.
Vitte JM, Davoult B, Roblot N, Mayer M, Joshi V, Courageot S, Tronche F, Vadrot J, Moreau MH, Kemeny F, Melki J.
Vitte JM, et al. Among authors: courageot s.
Am J Pathol. 2004 Nov;165(5):1731-41. doi: 10.1016/S0002-9440(10)63428-1.
Am J Pathol. 2004.
PMID: 15509541
Free PMC article.
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Activation of RNA metabolism-related genes in mouse but not human tissues deficient in SMN.
Olaso R, Joshi V, Fernandez J, Roblot N, Courageot S, Bonnefont JP, Melki J.
Olaso R, et al. Among authors: courageot s.
Physiol Genomics. 2006 Jan 12;24(2):97-104. doi: 10.1152/physiolgenomics.00134.2005. Epub 2005 Aug 23.
Physiol Genomics. 2006.
PMID: 16118268
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Bone marrow transplantation attenuates the myopathic phenotype of a muscular mouse model of spinal muscular atrophy.
Salah-Mohellibi N, Millet G, André-Schmutz I, Desforges B, Olaso R, Roblot N, Courageot S, Bensimon G, Cavazzana-Calvo M, Melki J.
Salah-Mohellibi N, et al. Among authors: courageot s.
Stem Cells. 2006 Dec;24(12):2723-32. doi: 10.1634/stemcells.2006-0170. Epub 2006 Aug 3.
Stem Cells. 2006.
PMID: 16888281
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