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Chronic Heavy Alcohol Use is Associated with Upregulated Paneth Cell Antimicrobials in Gastric Mucosa.
Clin Transl Gastroenterol. 2015 Jul 16;6(7):e103. doi: 10.1038/ctg.2015.26.
Clin Transl Gastroenterol. 2015.
PMID: 26181292
Free PMC article.
Human Endogenous Retroviruses: Residues of Ancient Times Are Differentially Expressed in Crohn's Disease.
Klag T, Courth L, Ostaff MJ, Ott G, Stange EF, Malek NP, Seifarth W, Wehkamp J.
Klag T, et al. Among authors: courth l.
Inflamm Intest Dis. 2019 Feb;3(3):125-137. doi: 10.1159/000494026. Epub 2018 Nov 21.
Inflamm Intest Dis. 2019.
PMID: 30820434
Free PMC article.
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Crohn's disease-derived monocytes fail to induce Paneth cell defensins.
Courth LF, Ostaff MJ, Mailänder-Sánchez D, Malek NP, Stange EF, Wehkamp J.
Courth LF, et al.
Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14000-5. doi: 10.1073/pnas.1510084112. Epub 2015 Oct 28.
Proc Natl Acad Sci U S A. 2015.
PMID: 26512113
Free PMC article.
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Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin.
Jaeger SU, Schroeder BO, Meyer-Hoffert U, Courth L, Fehr SN, Gersemann M, Stange EF, Wehkamp J.
Jaeger SU, et al. Among authors: courth l.
Mucosal Immunol. 2013 Nov;6(6):1179-90. doi: 10.1038/mi.2013.17. Epub 2013 Apr 10.
Mucosal Immunol. 2013.
PMID: 23571504
Free PMC article.
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β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor.
Klag T, Thomas M, Ehmann D, Courth L, Mailänder-Sanchez D, Weiss TS, Dayoub R, Abshagen K, Vollmar B, Thasler WE, Stange EF, Berg CP, Malek NP, Zanger UM, Wehkamp J.
Klag T, et al. Among authors: courth l.
Front Immunol. 2018 Jul 27;9:1735. doi: 10.3389/fimmu.2018.01735. eCollection 2018.
Front Immunol. 2018.
PMID: 30100908
Free PMC article.
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Bacterial Periplasmic Oxidoreductases Control the Activity of Oxidized Human Antimicrobial β-Defensin 1.
Wendler J, Ehmann D, Courth L, Schroeder BO, Malek NP, Wehkamp J.
Wendler J, et al. Among authors: courth l.
Infect Immun. 2018 Mar 22;86(4):e00875-17. doi: 10.1128/IAI.00875-17. Print 2018 Apr.
Infect Immun. 2018.
PMID: 29378796
Free PMC article.
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Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action.
Raschig J, Mailänder-Sánchez D, Berscheid A, Berger J, Strömstedt AA, Courth LF, Malek NP, Brötz-Oesterhelt H, Wehkamp J.
Raschig J, et al. Among authors: courth lf.
PLoS Pathog. 2017 Mar 21;13(3):e1006261. doi: 10.1371/journal.ppat.1006261. eCollection 2017 Mar.
PLoS Pathog. 2017.
PMID: 28323883
Free PMC article.
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Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.
Huhn S, da Silva Filho MI, Sanmuganantham T, Pichulik T, Catalano C, Pardini B, Naccarati A, Polakova-Vymetálkova V, Jiraskova K, Vodickova L, Vodicka P, Löffler MW, Courth L, Wehkamp J, Din FVN, Timofeeva M, Farrington SM, Jansen L, Hemminki K, Chang-Claude J, Brenner H, Hoffmeister M, Dunlop MG, Weber ANR, Försti A.
Huhn S, et al. Among authors: courth l.
PLoS One. 2018 Jun 21;13(6):e0199350. doi: 10.1371/journal.pone.0199350. eCollection 2018.
PLoS One. 2018.
PMID: 29928061
Free PMC article.
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