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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1992 2
1993 3
1994 2
1995 1
1997 4
1998 2
2000 3
2001 2
2002 2
2003 4
2004 8
2005 1
2006 3
2007 7
2008 4
2009 7
2010 4
2011 3
2012 8
2013 4
2014 3
2015 9
2016 8
2017 9
2018 6
2019 11
2020 12
2021 10
2022 16
2023 5
2024 4

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155 results

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Page 1
The COX10-AS1/miR-641/E2F6 Feedback Loop Is Involved in the Progression of Glioma.
Liu L, Li X, Wu H, Tang Y, Li X, Shi Y. Liu L, et al. Front Oncol. 2021 Jul 26;11:648152. doi: 10.3389/fonc.2021.648152. eCollection 2021. Front Oncol. 2021. PMID: 34381702 Free PMC article.
This study aimed to reveal the role and relevant mechanism of COX10-AS1 in glioma. The expression of COX10-AS1, miR-641 and E2F6 was measured by qRT-PCR and/or western blot. ...Moreover, further study indicated that E2F6 could promote COX10-AS1 expression by …
This study aimed to reveal the role and relevant mechanism of COX10-AS1 in glioma. The expression of COX10-AS1, miR-641 and E2 …
OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy.
Ahola S, Rivera Mejías P, Hermans S, Chandragiri S, Giavalisco P, Nolte H, Langer T. Ahola S, et al. Cell Metab. 2022 Nov 1;34(11):1875-1891.e7. doi: 10.1016/j.cmet.2022.08.017. Epub 2022 Sep 15. Cell Metab. 2022. PMID: 36113464 Free article.
Here, we demonstrate that the cardiac-specific loss of the assembly factor Cox10 of the cytochrome c oxidase causes mitochondrial cardiomyopathy in mice, which is associated with OXPHOS deficiency, lysosomal defects, and an aberrant mitochondrial morphology. Activation of …
Here, we demonstrate that the cardiac-specific loss of the assembly factor Cox10 of the cytochrome c oxidase causes mitochondrial car …
COX10-AS1-mediated miR-361-5p regulated cell invasion and migration by targeting SPRY1 in oral squamous cell carcinoma.
Deng J, Wu M. Deng J, et al. Am J Transl Res. 2023 Mar 15;15(3):2191-2206. eCollection 2023. Am J Transl Res. 2023. PMID: 37056821 Free PMC article.
Pearson's correlation analysis revealed a negative association between the expression of COX10-AS1 and that of miR-361-5p, and miR-361-5p transfection reduced COX10-AS1's influence on OSCC cell invasion and migration. Furthermore, COX10-AS1 favorably regulate …
Pearson's correlation analysis revealed a negative association between the expression of COX10-AS1 and that of miR-361-5p, and miR-36 …
Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion.
Mah-Som AY, Keppel MP, Tobin JM, Kolicheski A, Saucier N, Sexl V, French AR, Wagner JA, Fehniger TA, Cooper MA. Mah-Som AY, et al. Cell Rep. 2021 Jun 1;35(9):109209. doi: 10.1016/j.celrep.2021.109209. Cell Rep. 2021. PMID: 34077722 Free PMC article.
Ncr1-Cox10(delta/delta) mice had normal numbers of NK cells but impaired expansion of antigen-specific Ly49H(+) NK cells and impaired NK cell memory formation. Proliferation in vitro and homeostatic expansion were intact, indicating a specific metabolic requirement for ant …
Ncr1-Cox10(delta/delta) mice had normal numbers of NK cells but impaired expansion of antigen-specific Ly49H(+) NK cells and impaired …
COX10-AS1 Facilitates Cell Proliferation and Inhibits Cell Apoptosis in Glioblastoma Cells at Post-Transcription Level.
Zhou C, Jiang X, Liang A, Zhu R, Yang Y, Zhong L, Wan D. Zhou C, et al. Neurochem Res. 2020 Sep;45(9):2196-2203. doi: 10.1007/s11064-020-03081-4. Epub 2020 Aug 8. Neurochem Res. 2020. PMID: 32770454
Then, according to the results of bioinformatics analysis and mechanism assays including RIP, RNA pull down and luciferase reporter assay, ACTG1 was verified to be targeted by miR-361-5p in GBM. Next, COX10-AS1 (COX10 antisense RNA 1) was identified as an endogenous …
Then, according to the results of bioinformatics analysis and mechanism assays including RIP, RNA pull down and luciferase reporter assay, A …
Regulating COX10-AS1 / miR-142-5p / PAICS axis inhibits the proliferation of non-small cell lung cancer.
Tang X, Wu Y, Yang J, Zhu W. Tang X, et al. Bioengineered. 2021 Dec;12(1):4643-4653. doi: 10.1080/21655979.2021.1957072. Bioengineered. 2021. PMID: 34323174 Free PMC article.
Cell apoptosis detection showed that both the early and late apoptosis rates were increased after inhibition of COX10-AS1. Glycolysis cell-based assay also found that the content of L-lactate decreased significantly after using miR-142-5p mimics but increased after using s …
Cell apoptosis detection showed that both the early and late apoptosis rates were increased after inhibition of COX10-AS1. Glycolysis …
Biallelic COX10 Mutations and PMP22 Deletion in a Family With Leigh Syndrome and Hereditary Neuropathy With Liability to Pressure Palsy.
Kuroha Y, Ishiguro T, Tada M, Hara N, Murayama K, Kawachi I, Kasuga K, Miyashita A, Hasegawa A, Takahashi T, Matsubara N, Onodera O, Kakita A, Koike R, Ikeuchi T. Kuroha Y, et al. Neurol Genet. 2022 Sep 27;8(5):e200030. doi: 10.1212/NXG.0000000000200030. eCollection 2022 Oct. Neurol Genet. 2022. PMID: 36176336 Free PMC article.
Muscle biopsy revealed type 2 fiber uniformity and decreased staining of cytochrome c oxidase. The COX10 missense mutation was identified through whole-exome sequence. A 1.4-Mb genomic deletion extending from intron 5 of COX10 to PMP22 was detected. DISCUSSION: Thes …
Muscle biopsy revealed type 2 fiber uniformity and decreased staining of cytochrome c oxidase. The COX10 missense mutation was identi …
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M. Moschandrea C, et al. Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20. Nature. 2024. PMID: 38123683 Free PMC article.
Mice with specific ablation of the mitochondrial aspartyl-tRNA synthetase DARS2 (ref. (2)), the respiratory chain subunit SDHA(3) or the assembly factor COX10 (ref. (4)) in intestinal epithelial cells showed accumulation of large lipid droplets (LDs) in enterocytes of the …
Mice with specific ablation of the mitochondrial aspartyl-tRNA synthetase DARS2 (ref. (2)), the respiratory chain subunit SDHA(3) or the ass …
Adrenergic nerves activate an angio-metabolic switch in prostate cancer.
Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS. Zahalka AH, et al. Science. 2017 Oct 20;358(6361):321-326. doi: 10.1126/science.aah5072. Science. 2017. PMID: 29051371 Free PMC article.
We found that the loss of endothelial Adrb2, the gene encoding the beta(2)-adrenergic receptor, leads to inhibition of angiogenesis through enhancement of endothelial oxidative phosphorylation. Codeletion of Adrb2 and Cox10, a gene encoding a cytochrome IV oxidase assembly …
We found that the loss of endothelial Adrb2, the gene encoding the beta(2)-adrenergic receptor, leads to inhibition of angiogenesis through …
A Novel COX10 Deletion Polymorphism as a Susceptibility Factor for Sudden Cardiac Death Risk in Chinese Populations.
Yang Z, Zhang Q, Yu H, Li L, He Y, Zhu S, Li C, Zhang S, Luo B, Gao Y. Yang Z, et al. DNA Cell Biol. 2021 Jan;40(1):10-17. doi: 10.1089/dna.2020.6086. Epub 2020 Nov 11. DNA Cell Biol. 2021. PMID: 33180568
Identifying common genetic variations that are related to sudden cardiac death (SCD) is crucial since it can facilitate the diagnosis and risk stratification of SCD. It has been reported that COX10 mutations might be related with SCD. In this study, we performed a systemat …
Identifying common genetic variations that are related to sudden cardiac death (SCD) is crucial since it can facilitate the diagnosis and ri …
155 results