Crynen G - Search Results

1

Proximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host-directed antivirals.

Fang J, Pietzsch C, Witwit H, Tsaprailis G, Crynen G, Cho KF, Ting AY, Bukreyev A, Saphire EO, de la Torre JC. Fang J, et al. Among authors: crynen g. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2201208119. doi: 10.1073/pnas.2201208119. Epub 2022 Jul 18. Proc Natl Acad Sci U S A. 2022. PMID: 35858434 Free PMC article.

2

Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication.

Fang J, Pietzsch C, Tsaprailis G, Crynen G, Cho KF, Ting AY, Bukreyev A, de la Torre JC, Saphire EO. Fang J, et al. Among authors: crynen g. Cell Rep. 2022 Mar 22;38(12):110544. doi: 10.1016/j.celrep.2022.110544. Cell Rep. 2022. PMID: 35320713 Free PMC article.

3

Dyrk1a Mutations Cause Undergrowth of Cortical Pyramidal Neurons via Dysregulated Growth Factor Signaling.

Levy JA, LaFlamme CW, Tsaprailis G, Crynen G, Page DT. Levy JA, et al. Among authors: crynen g. Biol Psychiatry. 2021 Sep 1;90(5):295-306. doi: 10.1016/j.biopsych.2021.01.012. Epub 2021 Apr 8. Biol Psychiatry. 2021. PMID: 33840455 Free PMC article.

4

RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease.

Eshraghi M, Ramírez-Jarquín UN, Shahani N, Nuzzo T, De Rosa A, Swarnkar S, Galli N, Rivera O, Tsaprailis G, Scharager-Tapia C, Crynen G, Li Q, Thiolat ML, Bezard E, Usiello A, Subramaniam S. Eshraghi M, et al. Among authors: crynen g. Sci Adv. 2020 May 1;6(18):eaaz7001. doi: 10.1126/sciadv.aaz7001. eCollection 2020 May. Sci Adv. 2020. PMID: 32426479 Free PMC article.

5

Real-time digital polymerase chain reaction (PCR) as a novel technology improves limit of detection for rare allele assays.

Xu J, Duong K, Yang Z, Kaji K, Ou J, Head SR, Crynen G, Ordoukhanian P, Hanna L, Hanna A, Wang Y, Wang Z, Wang J. Xu J, et al. Among authors: crynen g. Transl Lung Cancer Res. 2021 Dec;10(12):4336-4352. doi: 10.21037/tlcr-21-728. Transl Lung Cancer Res. 2021. PMID: 35070745 Free PMC article.

6

Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.

Zhang P, Liu X, Abegg D, Tanaka T, Tong Y, Benhamou RI, Baisden J, Crynen G, Meyer SM, Cameron MD, Chatterjee AK, Adibekian A, Childs-Disney JL, Disney MD. Zhang P, et al. Among authors: crynen g. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055. doi: 10.1021/jacs.1c02248. Epub 2021 Aug 13. J Am Chem Soc. 2021. PMID: 34387474 Free PMC article.

7

Increased sensitivity using real-time dPCR for detection of SARS-CoV-2.

Duong K, Ou J, Li Z, Lv Z, Dong H, Hu T, Zhang Y, Hanna A, Gordon S, Crynen G, Head SR, Ordoukhanian P, Wang Y. Duong K, et al. Among authors: crynen g. Biotechniques. 2021 Jan;70(1):7-20. doi: 10.2144/btn-2020-0133. Epub 2020 Nov 23. Biotechniques. 2021. PMID: 33222514 Free PMC article.

8

Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions.

Haniff HS, Knerr L, Liu X, Crynen G, Boström J, Abegg D, Adibekian A, Lekah E, Wang KW, Cameron MD, Yildirim I, Lemurell M, Disney MD. Haniff HS, et al. Among authors: crynen g. Nat Chem. 2020 Oct;12(10):952-961. doi: 10.1038/s41557-020-0514-4. Epub 2020 Aug 24. Nat Chem. 2020. PMID: 32839603 Free PMC article.

9

Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA.

Ye F, Haniff HS, Suresh BM, Yang D, Zhang P, Crynen G, Teijaro CN, Yan W, Abegg D, Adibekian A, Shen B, Disney MD. Ye F, et al. Among authors: crynen g. ACS Chem Biol. 2022 Feb 18;17(2):474-482. doi: 10.1021/acschembio.1c00952. Epub 2022 Jan 19. ACS Chem Biol. 2022. PMID: 35044149 Free PMC article.

10

A Massively Parallel Selection of Small Molecule-RNA Motif Binding Partners Informs Design of an Antiviral from Sequence.

Childs-Disney JL, Tran T, Vummidi BR, Velagapudi SP, Haniff HS, Matsumoto Y, Crynen G, Southern MR, Biswas A, Wang ZF, Tellinghuisen TL, Disney MD. Childs-Disney JL, et al. Among authors: crynen g. Chem. 2018 Oct 11;4(10):2384-2404. doi: 10.1016/j.chempr.2018.08.003. Epub 2018 Sep 13. Chem. 2018. PMID: 30719503 Free PMC article.

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