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Virulence Characteristics of mecA-Positive Multidrug-Resistant Clinical Coagulase-Negative Staphylococci.
Chon JW, Lee UJ, Bensen R, West S, Paredes A, Lim J, Khan S, Hart ME, Phillips KS, Sung K. Chon JW, et al. Microorganisms. 2020 May 1;8(5):659. doi: 10.3390/microorganisms8050659. Microorganisms. 2020. PMID: 32369929 Free PMC article.
Measurement of their biofilm-forming ability and Spearman's rank correlation coefficient analyses revealed that the results of crystal violet (CV) and extracellular polymeric substances (EPS) assays were significantly correlated (rho = 0.9153, P = 3.612e-12). ...
Measurement of their biofilm-forming ability and Spearman's rank correlation coefficient analyses revealed that the results of crystal
Purification of proteins for crystallographic applications.
Bensen DC. Bensen DC. Methods Mol Biol. 2012;841:49-65. doi: 10.1007/978-1-61779-520-6_3. Methods Mol Biol. 2012. PMID: 22222448
One of the most important parameters correlated with success in protein crystallization experiments is sample purity and monodispersity. Heterologous expression systems have allowed investigators to produce engineered proteins in sufficient quantities which simplify the pu …
One of the most important parameters correlated with success in protein crystallization experiments is sample purity and monodispersi …
Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Bensen DC, Rodriguez S, Nix J, Cunningham ML, Tari LW. Bensen DC, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):382-5. doi: 10.1107/S1744309112006720. Epub 2012 Mar 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22505403 Free PMC article.
Despite possessing a high degree of sequence conservation with MurA enzymes from fosfomycin-susceptible organisms, recent microbiological studies suggest that MurA from Vibrio fischeri (VfiMurA) may confer fosfomycin resistance via a mechanism that is not yet understood. The c
Despite possessing a high degree of sequence conservation with MurA enzymes from fosfomycin-susceptible organisms, recent microbiological st …
Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.
Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Tari LW, et al. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. doi: 10.1016/j.bmcl.2006.10.086. Epub 2006 Nov 2. Bioorg Med Chem Lett. 2007. PMID: 17157005
The 2.25 A crystal structure of a complex of Aurora A kinase (AIKA) with cyclopropanecarboxylic acid-(3-(4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino)-phenyl)-amide 1 is described here. ...
The 2.25 A crystal structure of a complex of Aurora A kinase (AIKA) with cyclopropanecarboxylic acid-(3-(4-(3-trifluoromethyl-phenyla …