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Cyto-histologic correlation of crystal-storing histiocytosis: Rare presentation in breast, predating diagnosis of B-cell lymphoma by two years.
Firwana M, Clarke-Brodber AL, King RL, Dalland JC, Hartley CP, Boire NA, Sturgis CD. Firwana M, et al. Ann Diagn Pathol. 2022 Aug;59:151979. doi: 10.1016/j.anndiagpath.2022.151979. Epub 2022 May 18. Ann Diagn Pathol. 2022. PMID: 35609436
Crystal-storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of crystalized immunoglobulins within the cytoplasm of histiocytes. ...
Crystal-storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of crystalized immunoglobulins within …
Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition.
Wu WI, Voegtli WC, Sturgis HL, Dizon FP, Vigers GP, Brandhuber BJ. Wu WI, et al. PLoS One. 2010 Sep 23;5(9):e12913. doi: 10.1371/journal.pone.0012913. PLoS One. 2010. PMID: 20886116 Free PMC article.
They require the presence of both the pleckstrin-homology (PH) and kinase domains of AKT, but their binding mode has not yet been elucidated. We present here a 2.7 A resolution co-crystal structure of human AKT1 containing both the PH and kinase domains with a selective al …
They require the presence of both the pleckstrin-homology (PH) and kinase domains of AKT, but their binding mode has not yet been elucidated …
A dimerization hierarchy in the transmembrane domains of the HER receptor family.
Duneau JP, Vegh AP, Sturgis JN. Duneau JP, et al. Biochemistry. 2007 Feb 20;46(7):2010-9. doi: 10.1021/bi061436f. Epub 2007 Jan 25. Biochemistry. 2007. PMID: 17253768
We demonstrate, using a fluorescence-based measurement of interaction energies, a hierarchy of transmembrane domain interactions ranging from a noninteractive pair to strong dimerization. We propose a structural model based on the crystal structure of the EGFR dimer, to sh …
We demonstrate, using a fluorescence-based measurement of interaction energies, a hierarchy of transmembrane domain interactions ranging fro …
A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.
Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. ACS Chem Biol. 2017 Dec 15;12(12):3039-3048. doi: 10.1021/acschembio.7b00746. Epub 2017 Nov 14. ACS Chem Biol. 2017. PMID: 29096064 Free PMC article.
In AprA, the GNAT domain lacks both decarboxylation and acyl transfer activity. A crystal structure of the AprA MT1-GNAT di-domain with bound Mn(2+), malonate, and the methyl donor S-adenosylmethionine (SAM) reveals that the malonyl substrate is a bidentate metal ligand, i …
In AprA, the GNAT domain lacks both decarboxylation and acyl transfer activity. A crystal structure of the AprA MT1-GNAT di-domain wi …
Escherichia coli ykfE ORFan gene encodes a potent inhibitor of C-type lysozyme.
Monchois V, Abergel C, Sturgis J, Jeudy S, Claverie JM. Monchois V, et al. J Biol Chem. 2001 May 25;276(21):18437-41. doi: 10.1074/jbc.M010297200. Epub 2001 Feb 23. J Biol Chem. 2001. PMID: 11278658 Free article.
Under physiological conditions, the protein is a homodimer with a strong affinity for C-type lysozyme, as revealed by co-purification and co-crystallization. Activity measurements and fluorescence studies demonstrated that the YkfE gene product is a potent C-type lysozyme …
Under physiological conditions, the protein is a homodimer with a strong affinity for C-type lysozyme, as revealed by co-purification and co …
Facilitative capture of As(V), Pb(II) and methylene blue from aqueous solutions with MgO hybrid sponge-like carbonaceous composite derived from sugarcane leafy trash.
Li R, Liang W, Wang JJ, Gaston LA, Huang D, Huang H, Lei S, Awasthi MK, Zhou B, Xiao R, Zhang Z. Li R, et al. J Environ Manage. 2018 Apr 15;212:77-87. doi: 10.1016/j.jenvman.2017.12.034. Epub 2018 Feb 8. J Environ Manage. 2018. PMID: 29428656
Further FT-IR, XRD and XPS analysis demonstrated that the removal of As(V) by HSC was mainly dominated by surface deposition of MgHAsO(4) and Mg(H(2)AsO(4))(2) crystals on the HSC composite, while carbon pi-pi* transition and carbon pi-electron played key roles in Pb(II) a …
Further FT-IR, XRD and XPS analysis demonstrated that the removal of As(V) by HSC was mainly dominated by surface deposition of MgHAsO(4) an …
Recovery of phosphate and dissolved organic matter from aqueous solution using a novel CaO-MgO hybrid carbon composite and its feasibility in phosphorus recycling.
Li R, Wang JJ, Zhang Z, Awasthi MK, Du D, Dang P, Huang Q, Zhang Y, Wang L. Li R, et al. Sci Total Environ. 2018 Nov 15;642:526-536. doi: 10.1016/j.scitotenv.2018.06.092. Epub 2018 Jun 18. Sci Total Environ. 2018. PMID: 29908511
Characterization of composites after adsorption revealed the contributions of phosphate crystal deposition and electrostatic attraction on the phosphate uptake and involvement of pi - pi interaction in the humate adsorption. ...
Characterization of composites after adsorption revealed the contributions of phosphate crystal deposition and electrostatic attracti …