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2023 8
2024 2

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Safety and efficacy analyses across age and body mass index subgroups in East Asian participants with type 2 diabetes in the phase 3 tirzepatide studies (SURPASS programme).
Kiyosue A, Dunn JP, Cui X, Hickey A, Hirase T, Imaoka T, Heine RJ. Kiyosue A, et al. Diabetes Obes Metab. 2023 Apr;25(4):1056-1067. doi: 10.1111/dom.14952. Epub 2023 Jan 20. Diabetes Obes Metab. 2023. PMID: 36545807
MATERIALS AND METHODS: Data of participants enrolled in East Asian countries in the SURPASS-1, -3, -4, -5, J-mono and J-combo phase 3 clinical trials were included. Participants with type 2 diabetes with a baseline HbA1c of 7.0% up to 11.0% and a BMI of 23 kg/m(2) or great …
MATERIALS AND METHODS: Data of participants enrolled in East Asian countries in the SURPASS-1, -3, -4, -5, J-mono and J-combo phase 3 clinic …
A J-shaped relationship between ketones and the risk of diabetic kidney disease in patients with type 2 diabetes: New insights from a cross-sectional study.
Liu Y, Wang J, Xu F, Zhang S, Cui S, Li Y, Wang X, Zheng H, Li J, Kong Y, Yang J, Jiang X, Chang B. Liu Y, et al. Diabetes Obes Metab. 2023 Nov;25(11):3317-3326. doi: 10.1111/dom.15231. Epub 2023 Aug 22. Diabetes Obes Metab. 2023. PMID: 37608468
AIM: To investigate the association between circulating beta-hydroxybutyric acid (betaOHB) and diabetic kidney disease (DKD) risk in patients with type 2 diabetes (T2D). MATERIALS AND METHODS: A total of 1388 patients with T2D were recruited. ...
AIM: To investigate the association between circulating beta-hydroxybutyric acid (betaOHB) and diabetic kidney disease (DKD) risk in patient …
Diabetes, fasting blood glucose and the efficacy of remote ischaemic conditioning: A secondary analysis of the RICAMIS trial.
Zhang YN, Dai YJ, Cui Y, Wu Q, Zhang NN, Chen HS. Zhang YN, et al. Diabetes Obes Metab. 2023 Sep;25(9):2689-2696. doi: 10.1111/dom.15156. Epub 2023 Jun 8. Diabetes Obes Metab. 2023. PMID: 37288603
METHODS: A total of 1707 patients were enrolled in this post hoc study, including 535 patients with diabetes and 1172 without diabetes. Each group was further divided into RIC and control subgroups. ...CONCLUSION: Diabetes and FBG levels did not influence the …
METHODS: A total of 1707 patients were enrolled in this post hoc study, including 535 patients with diabetes and 1172 without diab …
Association Between Different Metabolic Markers and Metabolic Syndrome in an Outpatient Hyperuricemia Population: A Cross-Sectional Study.
Li X, Huang B, Liu Y, Wang M, Wang YX, Feng KL, Cui JQ. Li X, et al. Diabetes Metab Syndr Obes. 2023 Dec 4;16:3967-3978. doi: 10.2147/DMSO.S443472. eCollection 2023. Diabetes Metab Syndr Obes. 2023. PMID: 38077480 Free PMC article.
METHODS: A total of 399 hyperuricemia patients from Tianjin Medical University General Hospital from 2022 to 2023 were included in this study. We collected demographic, anthropometric, and biochemical data on each subject. ...
METHODS: A total of 399 hyperuricemia patients from Tianjin Medical University General Hospital from 2022 to 2023 were included in th …
Efficacy and safety of basal-first titration order in individuals with type 2 diabetes receiving short-term intensive insulin therapy: An exploratory analysis of BEYOND V.
Li Y, Yu D, Guo L, Mu Y, Wan H, Wang J, Xu B, Wang G, Jiang C, Liang L, Zhang J, Liu J, Zhang M, Cui N. Li Y, et al. Diabetes Obes Metab. 2023 May;25(5):1221-1228. doi: 10.1111/dom.14970. Epub 2023 Jan 19. Diabetes Obes Metab. 2023. PMID: 36594649
AIMS: To present the results of an exploratory analysis of the BEYOND V study in which Chinese individuals with uncontrolled type 2 diabetes (T2D) received short-term intensive insulin therapy (SIIT) during study run-in (prior to randomization) using a basal-first insulin …
AIMS: To present the results of an exploratory analysis of the BEYOND V study in which Chinese individuals with uncontrolled type 2 diabe …
A model-informed approach to accelerate the clinical development of cofrogliptin (HSK7653), a novel ultralong-acting dipeptidyl peptidase-4 inhibitor.
Cui C, Cao F, Kong II, Wu Q, Li F, Li H, Liu D. Cui C, et al. Diabetes Obes Metab. 2024 Feb;26(2):592-601. doi: 10.1111/dom.15348. Epub 2023 Nov 12. Diabetes Obes Metab. 2024. PMID: 37953687
AIM: To employ a model-informed drug development approach in facilitating decision making and expediting the clinical progress of cofrogliptin (HSK7653), a novel ultralong-acting dipeptidyl peptidase-4 (DPP-4) inhibitor, for the treatment of type 2 diabetes (T2D) via a biw …
AIM: To employ a model-informed drug development approach in facilitating decision making and expediting the clinical progress of cofroglipt …
Study on the Relationship and Predictive Value of First-Trimester Pregnancy-Associated Plasma Protein-A, Maternal Factors, and Biochemical Parameters in Gestational Diabetes Mellitus: A Large Case-Control Study in Southern China Mothers.
Cui J, Li P, Chen X, Li L, Ouyang L, Meng Z, Fan J. Cui J, et al. Diabetes Metab Syndr Obes. 2023 Apr 1;16:947-957. doi: 10.2147/DMSO.S398530. eCollection 2023. Diabetes Metab Syndr Obes. 2023. PMID: 37033400 Free PMC article.
OBJECTIVE: To investigate the relationship and predictive value of first-trimester pregnancy-associated plasma protein A (PAPP-A), maternal factors, and biochemical parameters with gestational diabetes mellitus (GDM) in southern China mothers. METHODS: This study recruited …
OBJECTIVE: To investigate the relationship and predictive value of first-trimester pregnancy-associated plasma protein A (PAPP-A), maternal …
Fractional Excretion of Urate is Positively Associated with Type 2 Diabetes in HUA Patients: A Cross-Sectional Study.
Huang B, Li X, Zhang X, Li S, Liu Y, Zhang M, Cui J. Huang B, et al. Diabetes Metab Syndr Obes. 2024 Apr 13;17:1701-1713. doi: 10.2147/DMSO.S454711. eCollection 2024. Diabetes Metab Syndr Obes. 2024. PMID: 38633278 Free PMC article.
PURPOSE: People with hyperuricemia (HUA) are often related to metabolic disorders such as diabetes, metabolic syndrome (MetS), and obesity. However, the correlation between excretion of uric acid and these diseases is unclear. Our study aimed to explore the relationship be …
PURPOSE: People with hyperuricemia (HUA) are often related to metabolic disorders such as diabetes, metabolic syndrome (MetS), and ob …