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Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.
Jacques S, van der Sloot AM, C Huard C, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD, Tyers M. Jacques S, et al. Among authors: culp ej. Genetics. 2020 Apr;214(4):1103-1120. doi: 10.1534/genetics.119.302851. Epub 2020 Feb 24. Genetics. 2020. PMID: 32094149 Free PMC article.
Ancient Antibiotics, Ancient Resistance.
Waglechner N, Culp EJ, Wright GD. Waglechner N, et al. Among authors: culp ej. EcoSal Plus. 2021 Mar;9(2). doi: 10.1128/ecosalplus.ESP-0027-2020. EcoSal Plus. 2021. PMID: 33734062 Review.
Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics.
Salamaga B, Kong L, Pasquina-Lemonche L, Lafage L, von Und Zur Muhlen M, Gibson JF, Grybchuk D, Tooke AK, Panchal V, Culp EJ, Tatham E, O'Kane ME, Catley TE, Renshaw SA, Wright GD, Plevka P, Bullough PA, Han A, Hobbs JK, Foster SJ. Salamaga B, et al. Among authors: culp ej. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2106022118. doi: 10.1073/pnas.2106022118. Proc Natl Acad Sci U S A. 2021. PMID: 34716264 Free PMC article.
21 results