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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 3
2001 2
2003 1
2004 5
2005 7
2006 7
2007 11
2008 15
2009 20
2010 25
2011 16
2012 18
2013 23
2014 26
2015 25
2016 21
2017 30
2018 26
2019 45
2020 48
2021 53
2022 57
2023 64
2024 31

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528 results

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Page 1
CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
Chang TM, Chiang YC, Lee CW, Lin CM, Fang ML, Chi MC, Liu JF, Kou YR. Chang TM, et al. Int J Biol Sci. 2023 Feb 27;19(5):1455-1470. doi: 10.7150/ijbs.79438. eCollection 2023. Int J Biol Sci. 2023. PMID: 37056937 Free PMC article.
However, few studies have explored the function of CXCL14 and its specific receptor in lung cancer metastasis. This study aims to determine the mechanism of CXCL14-promoted cancer metastasis. ...Conclusion: This study is the first to reveal the function of CXCL14 …
However, few studies have explored the function of CXCL14 and its specific receptor in lung cancer metastasis. This study aims to det …
Targetable Brg1-CXCL14 axis contributes to alcoholic liver injury by driving neutrophil trafficking.
Li N, Liu H, Xue Y, Xu Z, Miao X, Guo Y, Li Z, Fan Z, Xu Y. Li N, et al. EMBO Mol Med. 2023 Mar 8;15(3):e16592. doi: 10.15252/emmm.202216592. Epub 2023 Feb 1. EMBO Mol Med. 2023. PMID: 36722664 Free PMC article.
Flow cytometry showed that Brg1 deficiency specifically attenuated hepatic infiltration of Ly6G(+) neutrophils in the ALD mice. RNA-seq identified C-X-C motif chemokine ligand 14 (CXCL14) as a potential target for Brg1. CXCL14 knockdown alleviated whereas CXCL14 …
Flow cytometry showed that Brg1 deficiency specifically attenuated hepatic infiltration of Ly6G(+) neutrophils in the ALD mice. RNA-seq iden …
Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma.
Parikh A, Shin J, Faquin W, Lin DT, Tirosh I, Sunwoo JB, Puram SV. Parikh A, et al. J Immunother Cancer. 2020 Sep;8(2):e001048. doi: 10.1136/jitc-2020-001048. J Immunother Cancer. 2020. PMID: 32958684 Free PMC article.
Short hairpin RNA knockdown of CXCL14 was performed in mouse oral cavity (MOC)1 cells, and CXCL14 overexpression was performed in MOC2 cells. ...In a human tumor scRNA-seq cohort, we found that only malignant cell CXCL14, but not non-malignant cell or fibrobl …
Short hairpin RNA knockdown of CXCL14 was performed in mouse oral cavity (MOC)1 cells, and CXCL14 overexpression was performed …
Chemokine CXCL14; a double-edged sword in cancer development.
Gowhari Shabgah A, Haleem Al-Qaim Z, Markov A, Valerievich Yumashev A, Ezzatifar F, Ahmadi M, Mohammad Gheibihayat S, Gholizadeh Navashenaq J. Gowhari Shabgah A, et al. Int Immunopharmacol. 2021 Aug;97:107681. doi: 10.1016/j.intimp.2021.107681. Epub 2021 Apr 28. Int Immunopharmacol. 2021. PMID: 33932697 Review.
Depending on the type or origin of the tumor and components of the tumor microenvironment, CXCL14 plays a conflicting role in cancer. Although fibroblast-derived CXCL14 has a tumor-supportive role, epithelial-derived CXCL14 mainly inhibits tumor progression. …
Depending on the type or origin of the tumor and components of the tumor microenvironment, CXCL14 plays a conflicting role in cancer. …
Integrative analyses of scRNA-seq and scATAC-seq reveal CXCL14 as a key regulator of lymph node metastasis in breast cancer.
Xu K, Zhang W, Wang C, Hu L, Wang R, Wang C, Tang L, Zhou G, Zou B, Xie H, Tang J, Guan X. Xu K, et al. Hum Mol Genet. 2021 Apr 27;30(5):370-380. doi: 10.1093/hmg/ddab042. Hum Mol Genet. 2021. PMID: 33564857
We identified a novel cell subpopulation with an abnormally high expression level of CXCL14 in the PL of breast cancer patients. Cell trajectory analysis also revealed that CXCL14 was increased expressed in the late pseudo-time. Moreover, based on a tissue microarra …
We identified a novel cell subpopulation with an abnormally high expression level of CXCL14 in the PL of breast cancer patients. Cell …
CXCL14 as an emerging immune and inflammatory modulator.
Lu J, Chatterjee M, Schmid H, Beck S, Gawaz M. Lu J, et al. J Inflamm (Lond). 2016 Jan 5;13:1. doi: 10.1186/s12950-015-0109-9. eCollection 2016. J Inflamm (Lond). 2016. PMID: 26733763 Free PMC article. Review.
CXCL14 mainly contributes to the regulation of immune cell migration, also executes antimicrobial immunity. ...The present review summarizes the contribution of CXCL14 in these two aspects and discusses the biological mechanisms regulating CXCL14 expression a …
CXCL14 mainly contributes to the regulation of immune cell migration, also executes antimicrobial immunity. ...The present review sum …
CXCL14 Protects against Polymicrobial Sepsis by Enhancing Antibacterial Functions of Macrophages.
Lai X, Ding H, Yu R, Bai H, Liu Y, Cao J. Lai X, et al. Am J Respir Cell Mol Biol. 2022 Nov;67(5):589-601. doi: 10.1165/rcmb.2022-0249OC. Am J Respir Cell Mol Biol. 2022. PMID: 35926119
Here, the impact of CXCL14/CXCR4 blockade or CXCL14 administration on sepsis was assessed using murine and cell models, as well as human samples. ...In vivo, CXCL14 blockade using anti-CXCL14 antibody or CXCL14 knockdown by adeno-associated viru …
Here, the impact of CXCL14/CXCR4 blockade or CXCL14 administration on sepsis was assessed using murine and cell models, as wel …
Fibroblast-derived CXCL14 aggravates crystalline silica-induced pulmonary fibrosis by mediating polarization and recruitment of interstitial macrophages.
You Y, Yuan H, Min H, Li C, Chen J. You Y, et al. J Hazard Mater. 2023 Oct 15;460:132489. doi: 10.1016/j.jhazmat.2023.132489. Epub 2023 Sep 8. J Hazard Mater. 2023. PMID: 37688871
Furthermore, in vivo studies echoed that systemic CXCL14 neutralizing or fibroblast-specific Cxcl14 knockout proved CXCL14 was indispensable for the recruitment and phenotype alteration of lung macrophages, especially interstitial macrophages (IMs), under sti …
Furthermore, in vivo studies echoed that systemic CXCL14 neutralizing or fibroblast-specific Cxcl14 knockout proved CXCL14 …
CXCL14 antagonizes the CXCL12-CXCR4 signaling axis.
Hara T, Tanegashima K. Hara T, et al. Biomol Concepts. 2014 May;5(2):167-73. doi: 10.1515/bmc-2014-0007. Biomol Concepts. 2014. PMID: 25372750 Free article. Review.
CXCL12 and CXCL14 are evolutionarily conserved members of the CXC-type chemokine family. ...In fact, a stabilized dimeric peptide containing the C-terminal 51-77 amino acid residues of CXCL14 has been shown to have stronger CXCL12 antagonistic activity than full-len …
CXCL12 and CXCL14 are evolutionarily conserved members of the CXC-type chemokine family. ...In fact, a stabilized dimeric peptide con …
CXCL14 as a potential marker for immunotherapy response prediction in renal cell carcinoma.
Pan Q, Liu R, Zhang X, Cai L, Li Y, Dong P, Gao J, Liu Y, He L. Pan Q, et al. Ther Adv Med Oncol. 2023 Dec 25;15:17588359231217966. doi: 10.1177/17588359231217966. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 38152696 Free PMC article.
The expression level of CXCL14 was associated with CXCR4 expression in RCC. CONCLUSION: CXCL14 expression is associated with immunotherapy response in RCC. ...Fibroblasts with CXCL14 were present in patients responding to immunotherapy. Further tests confirme …
The expression level of CXCL14 was associated with CXCR4 expression in RCC. CONCLUSION: CXCL14 expression is associated with i …
528 results