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1999 1
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2015 7
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Page 1
CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner.
Broxmeyer HE, Cooper SH, Ropa J. Broxmeyer HE, et al. Blood Cells Mol Dis. 2021 Nov;91:102594. doi: 10.1016/j.bcmd.2021.102594. Epub 2021 Jul 3. Blood Cells Mol Dis. 2021. PMID: 34520986 Free PMC article.
This suggests that CXCL15/Lungkine acts as a negative regulator of the cell cycling of these HPCs in vivo. ...This clearly identifies the negative regulatory activity of CXCL15/Lungkine on proliferation of multiple types of mouse HPCs....
This suggests that CXCL15/Lungkine acts as a negative regulator of the cell cycling of these HPCs in vivo. ...This clearly identifies …
The Effect of Hypoxia on the Expression of CXC Chemokines and CXC Chemokine Receptors-A Review of Literature.
Korbecki J, Kojder K, Kapczuk P, Kupnicka P, Gawrońska-Szklarz B, Gutowska I, Chlubek D, Baranowska-Bosiacka I. Korbecki J, et al. Int J Mol Sci. 2021 Jan 15;22(2):843. doi: 10.3390/ijms22020843. Int J Mol Sci. 2021. PMID: 33467722 Free PMC article. Review.
This paper reviews all available information on hypoxia-induced changes in the expression of all CXC chemokines (CXCL1, CXCL2, CXCL3, CXCL4, CXCL5, CXCL6, CXCL7, CXCL8 (IL-8), CXCL9, CXCL10, CXCL11, CXCL12 (SDF-1), CXCL13, CXCL14, CXCL15, CXCL16, CXCL17) as well as CXC che …
This paper reviews all available information on hypoxia-induced changes in the expression of all CXC chemokines (CXCL1, CXCL2, CXCL3, CXCL4, …
Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression.
Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, Korman AJ, Christiano AM, De Marzo AM, Drake CG. Lopez-Bujanda ZA, et al. Nat Cancer. 2021 Aug;2(8):803-818. doi: 10.1038/s43018-021-00227-3. Epub 2021 Jul 19. Nat Cancer. 2021. PMID: 35122025 Free PMC article.
We found that castration resulted in increased expression of interleukin-8 (IL-8) and its probable murine homolog Cxcl15 in prostate epithelial cells. We showed that these chemokines drove subsequent intratumoral infiltration of tumor-promoting polymorphonuclear myeloid-de …
We found that castration resulted in increased expression of interleukin-8 (IL-8) and its probable murine homolog Cxcl15 in prostate …
A novel bovine CXCL15 gene in the GRO chemokine gene cluster.
Zhu JJ, Canter JA, Rodriguez LL, Arzt J. Zhu JJ, et al. Vet Immunol Immunopathol. 2020 Feb;220:109990. doi: 10.1016/j.vetimm.2019.109990. Epub 2019 Dec 10. Vet Immunol Immunopathol. 2020. PMID: 31855743
Phylogenetic analysis and gene structures showed that CXCL15 is closer to CXCL8 than to other ELR+ CXCLs. Our microarray data show that bovine CXCL15 expression was higher in laser capture micro-dissected bovine pharyngeal epithelia than in the whole pharyngeal tiss …
Phylogenetic analysis and gene structures showed that CXCL15 is closer to CXCL8 than to other ELR+ CXCLs. Our microarray data show th …
Expression of CXCL15 (Lungkine) in murine gastrointestinal, urogenital, and endocrine organs.
Schmitz JM, McCracken VJ, Dimmitt RA, Lorenz RG. Schmitz JM, et al. J Histochem Cytochem. 2007 May;55(5):515-24. doi: 10.1369/jhc.6A7121.2007. Epub 2007 Jan 22. J Histochem Cytochem. 2007. PMID: 17242461
Our results indicate that CXCL15 is expressed throughout the gastrointestinal tract, with the exception of the cecum. ...Similar to the increased expression of CXCL15 during pulmonary inflammation, gastric inflammation induced by infection with Helicobacter felis ca …
Our results indicate that CXCL15 is expressed throughout the gastrointestinal tract, with the exception of the cecum. ...Similar to t …
Tumor-derived OBP2A promotes prostate cancer castration resistance.
Jeong JH, Zhong S, Li F, Huang C, Chen X, Liu Q, Peng S, Park H, Lee YM, Dhillon J, Luo JL. Jeong JH, et al. J Exp Med. 2023 Mar 6;220(3):e20211546. doi: 10.1084/jem.20211546. Epub 2022 Dec 22. J Exp Med. 2023. PMID: 36547668 Free PMC article.
Here, we report that odorant-binding protein (OBP2A) released from tumors in remission during ADT catches survival factors, such as CXCL15/IL8, to promote PCa cell androgen-independent growth and enhance the infiltration of myeloid-derived suppressor cells (MDSCs) into tum …
Here, we report that odorant-binding protein (OBP2A) released from tumors in remission during ADT catches survival factors, such as CXCL1 …
Hydrogen peroxide-induced oxidative stress promotes expression of CXCL15/Lungkine mRNA in a MEK/ERK-dependent manner in fibroblast-like synoviocytes derived from mouse temporomandibular joint.
Asanuma K, Yokota S, Chosa N, Kamo M, Ibi M, Mayama H, Irié T, Satoh K, Ishisaki A. Asanuma K, et al. J Oral Biosci. 2023 Mar;65(1):97-103. doi: 10.1016/j.job.2022.12.002. Epub 2022 Dec 28. J Oral Biosci. 2023. PMID: 36584898 Free article.
RESULTS: Hydrogen peroxide (H(2)O(2)) treatment significantly promoted mRNA expression of neutrophil chemoattractant CXCL15/Lungkine in a dose-dependent manner (100-500 muM) in fibroblast-like synoviocytes (FLSs) derived from mouse TMJ. ...CONCLUSIONS: H(2)O(2)-induced oxi …
RESULTS: Hydrogen peroxide (H(2)O(2)) treatment significantly promoted mRNA expression of neutrophil chemoattractant CXCL15/Lungkine …
Lysophosphatidic acid induces interleukin-6 and CXCL15 secretion from MLO-Y4 cells through activation of the LPA(1) receptor and PKCteta signaling pathway.
Wu X, Ma Y, Chen H, Hao Z, Su N, Li X, Shen J, Wang H. Wu X, et al. Int Immunopharmacol. 2019 Sep;74:105664. doi: 10.1016/j.intimp.2019.05.049. Epub 2019 Jun 21. Int Immunopharmacol. 2019. PMID: 31233937
In this study, we report that LPA markedly enhanced IL-6 and CXCL15 (mouse homologue of human IL-8) production in MLO-Y4 cells and that this enhancement was suppressed by the LPA(1/3)-selective antagonist Ki16425, the G(i/o) protein inhibitor PTX or the protein kinase C (P …
In this study, we report that LPA markedly enhanced IL-6 and CXCL15 (mouse homologue of human IL-8) production in MLO-Y4 cells and th …
Different Responses to Identical Trauma Between BALB/C and C57BL/6 Mice.
Chen X, Cheng C, Cheng W, Wang Y, Zuo X, Tang W, Yu Z, Yang Z, Wang Z, Zhu P, Huang W. Chen X, et al. Med Sci Monit. 2021 Feb 23;27:e928676. doi: 10.12659/MSM.928676. Med Sci Monit. 2021. PMID: 33621218 Free PMC article.
We measured mortality rate, pulmonary microvascular permeability, and Cxcl15 gene expression in BALB/C and C57BL/6 mice before and after blast-wave injury. ...The level of Cxcl15 expression in BALB/C mice was higher than in C57BL/6 mice before and after injury, and …
We measured mortality rate, pulmonary microvascular permeability, and Cxcl15 gene expression in BALB/C and C57BL/6 mice before and af …
58 results