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Cyclamen europaeum extract for acute sinusitis.
Zalmanovici Trestioreanu A, Barua A, Pertzov B. Zalmanovici Trestioreanu A, et al. Cochrane Database Syst Rev. 2018 May 11;5(5):CD011341. doi: 10.1002/14651858.CD011341.pub2. Cochrane Database Syst Rev. 2018. PMID: 29750825 Free PMC article. Review.
OBJECTIVES: To assess the effectiveness of topical intranasal Cyclamen europaeum extract on clinical response in adults and children with acute sinusitis. ...AUTHORS' CONCLUSIONS: The effectiveness of Cyclamen europaeum for people with acute sinusitis …
OBJECTIVES: To assess the effectiveness of topical intranasal Cyclamen europaeum extract on clinical response in adults and ch …
Lyophilized Cyclamen europaeum tuber extract in the treatment of rhinosinusitis.
Jurkiewicz D, Hassmann-Poznańska E, Kaźmierczak H, Składzień J, Pietruszewska W, Burduk P, Rapiejko P. Jurkiewicz D, et al. Otolaryngol Pol. 2016 Feb 29;70(1):1-9. doi: 10.5604/00306657.1195609. Otolaryngol Pol. 2016. PMID: 26926302
The goal of this article is to present the current knowledge on the use of intranasal preparations containing natural saponin fractions from the rhizomes of Alpine cyclamen (Cyclamen europaeum). Saponins contained in the extract of Alpine cyclamen ( …
The goal of this article is to present the current knowledge on the use of intranasal preparations containing natural saponin fractions from …
Cyclamen europaeum improves the effect of oral antibiotics on exacerbations and recurrences of chronic rhinosinusitis: a real-life observational study (CHRONOS).
Lopatin AS, Ivanchenko OA, Soshnikov SS, Mullol J. Lopatin AS, et al. Acta Otorhinolaryngol Ital. 2018 Apr;38(2):115-123. doi: 10.14639/0392-100X-1342. Acta Otorhinolaryngol Ital. 2018. PMID: 29967550 Free PMC article.
Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and paranasal sinuses affecting 11% of the European population. Cyclamen europaeum plant extract (CE) has demonstrated efficacy in treating acute rhinosinusitis, but its role in CRS exacerbations re …
Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and paranasal sinuses affecting 11% of the European population. Cycla …
Ex-Vivo and In-Vivo Assessment of Cyclamen europaeum Extract After Nasal Administration.
Fernández-Campos F, Clares B, Rodríguez-Lagunas MJ, Jauregui O, Casals I, Calpena AC. Fernández-Campos F, et al. Pharmaceutics. 2019 Aug 21;11(9):426. doi: 10.3390/pharmaceutics11090426. Pharmaceutics. 2019. PMID: 31438642 Free PMC article.
Rhinosinusitis is a prevalent disorder with a severe impact on the health-related quality of life. Saponins of Cyclamen europaeum exert a clinically proven curative effect on rhinosinusitis symptoms when instilled into the nasal cavity, however, more extensive precl …
Rhinosinusitis is a prevalent disorder with a severe impact on the health-related quality of life. Saponins of Cyclamen europaeum …
Pharmacoeconomics of Cyclamen europaeum in the management of acute rhinosinusitis.
Mullol J, Crespo C, Carré C, Brosa M. Mullol J, et al. Laryngoscope. 2013 Nov;123(11):2620-5. doi: 10.1002/lary.24167. Epub 2013 May 13. Laryngoscope. 2013. PMID: 23670920
OBJECTIVES/HYPOTHESIS: To carry out a pharmacoeconomic analysis of Cyclamen europaeum (CE) in the management of acute rhinosinusitis (ARS) in Spain using data from the PROSINUS (PROspective epidemiological study of the diagnosis and treatment of acute rhinoSINUSitis …
OBJECTIVES/HYPOTHESIS: To carry out a pharmacoeconomic analysis of Cyclamen europaeum (CE) in the management of acute rhinosin …
An exploratory trial of Cyclamen europaeum extract for acute rhinosinusitis.
Ponikau JU, Hamilos DL, Barreto A, Cecil J, Jones SW, Manthei SE, Collins J. Ponikau JU, et al. Laryngoscope. 2012 Sep;122(9):1887-92. doi: 10.1002/lary.23366. Epub 2012 Jun 6. Laryngoscope. 2012. PMID: 22674586 Clinical Trial.
Cyclamen treatment was well tolerated. CONCLUSIONS: Cyclamen treatment significantly reduced sinus opacification in patients with acute rhinosinusitis. Further exploration of Cyclamen treatment in larger patient populations is warranted....
Cyclamen treatment was well tolerated. CONCLUSIONS: Cyclamen treatment significantly reduced sinus opacification in patients w …
Cyclamen europaeum nasal spray, a novel phytotherapeutic product for the management of acute rhinosinusitis: a randomized double-blind, placebo-controlled trial.
Pfaar O, Mullol J, Anders C, Hörmann K, Klimek L. Pfaar O, et al. Rhinology. 2012 Mar;50(1):37-44. doi: 10.4193/Rhino11.141. Rhinology. 2012. PMID: 22469604 Clinical Trial.
AIM: To evaluate the efficacy and safety of a phytotherapeutic nasal spray containing Cyclamen europaeum (CE) in the treatment of acute rhinosinusitis (ARS). ...
AIM: To evaluate the efficacy and safety of a phytotherapeutic nasal spray containing Cyclamen europaeum (CE) in the treatment …
Intranasal immunization of guinea pig with trivalent influenza antigen adjuvanted by Cyclamen europaeum tubers extract.
Evseenko VA, Kolosova NP, Gudymo AS, Maltsev SV, Bulanovich JA, Goncharova NI, Danilchenko NV, Marchenko VY, Susloparov IM, Ryzhikov AB. Evseenko VA, et al. Arch Virol. 2019 Jan;164(1):243-247. doi: 10.1007/s00705-018-4023-3. Epub 2018 Sep 17. Arch Virol. 2019. PMID: 30225522
Cyclamen europaeum tubers extract (CTE) with concentration commonly used for human rhinosinusitis treatment was tested as mucosal adjuvant in experimental intranasal immunization of guinea pigs with concentrated commercially available influenza trivalent vaccine and …
Cyclamen europaeum tubers extract (CTE) with concentration commonly used for human rhinosinusitis treatment was tested as muco …
Trends on rhinosinusitis diagnosis and treatment.
Mullol J. Mullol J. Otolaryngol Pol. 2009 Sep;63(7):3-4. doi: 10.1016/S0030-6657(09)70179-9. Otolaryngol Pol. 2009. PMID: 20564891
Recent, epidemiological PROSINUS study of ARS, carried out in Spain, is also briefly reviewed, with special emphasis on Cyclamen europaeum extract use in ARS treatment. A new treatment approach is proposed, based on Cyclamen europaeum extract use in AR …
Recent, epidemiological PROSINUS study of ARS, carried out in Spain, is also briefly reviewed, with special emphasis on Cyclamen e …
[A Systematic Review of Phytotherapy for Acute Rhinosinusitis].
Koch AK, Klose P, Lauche R, Cramer H, Baasch J, Dobos GJ, Langhorst J. Koch AK, et al. Forsch Komplementmed. 2016;23(3):165-9. doi: 10.1159/000447467. Epub 2016 Jun 23. Forsch Komplementmed. 2016. PMID: 27404100 Review. German.
Seven trials on Pelargonium sidoides (EPs 7630, Umckaloabo), Myrtol (GeloMyrtol forte), BNO 1016 (Sinupret extract), BNO 101 (Sinupret), Cyclamen europaeum (Nasodren), and Esberitox were included. Risk of bias was heterogeneous. ...Myrtol showed benefits against a p …
Seven trials on Pelargonium sidoides (EPs 7630, Umckaloabo), Myrtol (GeloMyrtol forte), BNO 1016 (Sinupret extract), BNO 101 (Sinupret), …
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