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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 6
1976 17
1977 14
1978 13
1979 20
1980 23
1981 17
1982 18
1983 22
1984 14
1985 20
1986 15
1987 19
1988 16
1989 11
1990 22
1991 13
1992 10
1993 16
1994 9
1995 16
1996 7
1997 13
1998 18
1999 15
2000 15
2001 24
2002 33
2003 46
2004 52
2005 37
2006 59
2007 65
2008 46
2009 64
2010 75
2011 80
2012 100
2013 115
2014 107
2015 111
2016 120
2017 114
2018 107
2019 101
2020 109
2021 103
2022 86
2023 79
2024 27

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1,990 results

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Page 1
Regulation of the extrarenal CYP27B1-hydroxylase.
Adams JS, Rafison B, Witzel S, Reyes RE, Shieh A, Chun R, Zavala K, Hewison M, Liu PT. Adams JS, et al. J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:22-7. doi: 10.1016/j.jsbmb.2013.12.009. Epub 2013 Dec 31. J Steroid Biochem Mol Biol. 2014. PMID: 24388948 Free PMC article. Review.
Provided here is a collective review of research on the extrarenal CYP27B1-hydroxylase that shapes our current and expanding vision of the role this enzyme plays in the intracrinology and paracrinology, as opposed to the traditional endocrinology, of vitamin D to regulate …
Provided here is a collective review of research on the extrarenal CYP27B1-hydroxylase that shapes our current and expanding vision o …
Vitamin D receptor (VDR) and metabolizing enzymes CYP27B1 and CYP24A1 in breast cancer.
Voutsadakis IA. Voutsadakis IA. Mol Biol Rep. 2020 Dec;47(12):9821-9830. doi: 10.1007/s11033-020-05780-1. Epub 2020 Dec 1. Mol Biol Rep. 2020. PMID: 33259013 Review.
In addition, it is commonly expressed in breast cancer and has tumor suppressive effects. Cytochrome enzymes CYP27B1 and CYP24A1 that perform the final conversion of the circulating form of vitamin D, 25-hydroxyvitamin D (25-OHD) to the active VDR ligand, 1a, …
In addition, it is commonly expressed in breast cancer and has tumor suppressive effects. Cytochrome enzymes CYP27B1 and CYP24A1 that …
Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression.
Meyer MB, Pike JW. Meyer MB, et al. J Steroid Biochem Mol Biol. 2020 Feb;196:105500. doi: 10.1016/j.jsbmb.2019.105500. Epub 2019 Oct 16. J Steroid Biochem Mol Biol. 2020. PMID: 31629064 Free PMC article. Review.
Cyp27b1 and Cyp24a1 are reciprocally regulated in the kidney by the key hormones PTH, FGF23, and 1,25(OH)(2)D(3). ...Deletion of both M1 and M21 submodules together fully eliminates basal Cyp27b1 expression in the kidney, leading to a systemic and skeletal phenotype …
Cyp27b1 and Cyp24a1 are reciprocally regulated in the kidney by the key hormones PTH, FGF23, and 1,25(OH)(2)D(3). ...Deletion of both …
CYP27B1 Gene Polymorphism rs10877012 in Patients Diagnosed with Colorectal Cancer.
Latacz M, Snarska J, Kostyra E, Wroński K, Fiedorowicz E, Savelkoul H, Jarmołowska B, Płomiński J, Grzybowski R, Cieślińska A. Latacz M, et al. Nutrients. 2020 Apr 3;12(4):998. doi: 10.3390/nu12040998. Nutrients. 2020. PMID: 32260235 Free PMC article.
In this study, we investigated the association of rs10877012 (T/G) polymorphism in the CYP27B1 gene with CRC susceptibility. The study population (n = 325) included CRC patients (n = 106) and healthy controls (n = 219). DNA was extracted from peripheral leukocytes and anal …
In this study, we investigated the association of rs10877012 (T/G) polymorphism in the CYP27B1 gene with CRC susceptibility. The stud …
Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.
Latacz M, Snarska J, Kostyra E, Fiedorowicz E, Savelkoul HF, Grzybowski R, Cieślińska A. Latacz M, et al. Nutrients. 2020 Mar 18;12(3):801. doi: 10.3390/nu12030801. Nutrients. 2020. PMID: 32197412 Free PMC article. Review.
Modern literature lacks complete information on polymorphisms in CYP27B1, the only enzyme capable of vitamin D activation. This review presents gathered data that relate to genetic variants in CYP27B1 gene in correlation to multiple diseases, mostly concerning color …
Modern literature lacks complete information on polymorphisms in CYP27B1, the only enzyme capable of vitamin D activation. This revie …
Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24).
Inouye K, Sakaki T. Inouye K, et al. Biotechnol Annu Rev. 2001;7:179-94. doi: 10.1016/s1387-2656(01)07037-5. Biotechnol Annu Rev. 2001. PMID: 11686044 Review.
The key enzymes of vitamin D3 metabolism, renal 25-hydroxyvitamin D3 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24) were expressed in Escherichia coli, and their enzymatic properties were revealed. ...Unexpectedly, …
The key enzymes of vitamin D3 metabolism, renal 25-hydroxyvitamin D3 1 alpha-hydroxylase ( …
The role of vitamin D-synthesizing enzyme CYP27B1 in systemic lupus erythematosus.
Luo M, Lıu J, Yuan Y, Chen Y, Yuan G. Luo M, et al. Turk J Med Sci. 2022 Aug;52(4):984-989. doi: 10.55730/1300-0144.53899. Epub 2022 Aug 10. Turk J Med Sci. 2022. PMID: 36326421 Free PMC article.
BACKGROUND: To measure the expression of 1alpha-hydroxylase (CYP27B1) and serum 25(OH)D concentration in systemic lupus erythematosus (SLE) and to investigate the role of CYP27B1 in SLE. ...Among SLE patients, the prevalence of lupus nephritis was higher in a subgro …
BACKGROUND: To measure the expression of 1alpha-hydroxylase (CYP27B1) and serum 25(OH)D concentration in systemic lupus erythematosus …
Vitamin D-dependent rickets (VDDR) type 1: case series of two siblings with a CYP27B1 mutation and review of the literature.
Dhull RS, Jain R, Deepthi B, Cheong HI, Saha A, Mehndiratta M, Basu S. Dhull RS, et al. J Bras Nefrol. 2020 Oct-Dec;42(4):494-497. doi: 10.1590/2175-8239-JBN-2020-0001. J Bras Nefrol. 2020. PMID: 32926064 Free PMC article. Review.
There was no improvement initially, hence the siblings were reinvestigated and later diagnosed as having vitamin D-dependent rickets (VDDR) type 1 due to a rare mutation in the CYP27B1 gene encoding the 1alpha-hydroxylase enzyme. Both siblings improved with calcitriol supp …
There was no improvement initially, hence the siblings were reinvestigated and later diagnosed as having vitamin D-dependent rickets (VDDR) …
Vitamin D action: lessons from VDR and Cyp27b1 null mice.
Bouillon R, Lieben L, Mathieu C, Verstuyf A, Carmeliet G. Bouillon R, et al. Pediatr Endocrinol Rev. 2013 Jun;10 Suppl 2:354-66. Pediatr Endocrinol Rev. 2013. PMID: 23858619 Review.
These findings have resulted in clear clinical guidelines for the treatment of vitamin D-related bone diseases of infants, children and adults. Tissue-specific VDR or Cyp27b1 deletion in mice has also proven to be useful to define the precise role of 1,25(OH)2D action in c …
These findings have resulted in clear clinical guidelines for the treatment of vitamin D-related bone diseases of infants, children and adul …
Expression of Rat Cyp27b1 in HepG2 Cells Using Adenovirus Vector and Its Application to Evaluation of Self-Made and Commercially Available Anti-Cyp27b1 Antibodies.
Nagao C, Kise S, Iijima A, Okada T, Nakanishi T, Sato S, Nishikawa M, Ikushiro S, Yasuda K, Sakaki T. Nagao C, et al. J Nutr Sci Vitaminol (Tokyo). 2023;69(2):90-97. doi: 10.3177/jnsv.69.90. J Nutr Sci Vitaminol (Tokyo). 2023. PMID: 37121728 Free article.
Western blot analysis using an anti-Flag antibody showed a clear band of Cyp27b1-Flag. Next, we screened three types of anti-Cyp27b1 antibodies, which consist of two commercially available antibodies and our self-made antibody using Cyp27b1- or Cyp27b1 …
Western blot analysis using an anti-Flag antibody showed a clear band of Cyp27b1-Flag. Next, we screened three types of anti-Cyp27 …
1,990 results