Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1996 1
1997 1
2001 1
2003 3
2005 2
2006 4
2007 3
2008 5
2009 2
2010 2
2011 3
2012 3
2013 2
2014 3
2015 4
2016 1
2017 1
2018 4
2019 2
2020 2
2021 1
2022 2
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

45 results

Results by year

Filters applied: . Clear all
Page 1
Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.
Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW. Anakk S, et al. FASEB J. 2003 Sep;17(12):1736-8. doi: 10.1096/fj.02-1004fje. Epub 2003 Jul 3. FASEB J. 2003. PMID: 12958193
We report that CYP3a13 gene, located on mouse chromosome 5, spans 27.5 Kb and contains 13 exons. ...CYP3a13 shows a broad tissue distribution with predominant expression in liver. ...
We report that CYP3a13 gene, located on mouse chromosome 5, spans 27.5 Kb and contains 13 exons. ...CYP3a13 shows a broad tiss …
Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver.
Down MJ, Arkle S, Mills JJ. Down MJ, et al. Arch Biochem Biophys. 2007 Jan 1;457(1):105-10. doi: 10.1016/j.abb.2006.09.017. Epub 2006 Oct 6. Arch Biochem Biophys. 2007. PMID: 17107656
This study reports that dexamethasone (DEX) significantly induces CYP3A11, CYP3A13 and CYP3A25 mRNA expression in male and female 4 days, 3 weeks and 18 weeks old C57BL/6J mice. ...
This study reports that dexamethasone (DEX) significantly induces CYP3A11, CYP3A13 and CYP3A25 mRNA expression in male and female 4 d …
Mouse aortic muscle cells respond to oxygen following cytochrome P450 3A13 gene transfer.
Ciofini E, Scebba F, Luin S, Sodini D, Angeloni D, Coceani F. Ciofini E, et al. Can J Physiol Pharmacol. 2013 May;91(5):369-74. doi: 10.1139/cjpp-2012-0370. Epub 2013 Jan 2. Can J Physiol Pharmacol. 2013. PMID: 23656416
Furthermore, this oxygen effect was curtailed by the ET-1/ETA receptor antagonist BQ-123. We also found that CYP3A13 occurs naturally in aortic tissue and its isolated muscle cells in culture. We conclude that CYP3A13 is involved in oxygen sensing, and its action in …
Furthermore, this oxygen effect was curtailed by the ET-1/ETA receptor antagonist BQ-123. We also found that CYP3A13 occurs naturally …
A map of the mouse Cyp3a locus.
Zaphiropoulos PG. Zaphiropoulos PG. DNA Seq. 2003 Jun;14(3):155-62. doi: 10.1080/1042517031000089478. DNA Seq. 2003. PMID: 14509827
The mouse Cyp3a locus on chromosome 5 was analyzed by the use of bacterial artificial chromosomes. Five out of the six known Cyp3a genes, Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41 and Cyp3a44 were found to be linked to each other, however, Cyp3a13, possibly becaus …
The mouse Cyp3a locus on chromosome 5 was analyzed by the use of bacterial artificial chromosomes. Five out of the six known Cyp3a genes, Cy …
Heat stress delays detoxification of phenanthrene in the springtail Folsomia candida.
Dai W, Holmstrup M, Slotsbo S, Bakker R, Damgaard C, van Gestel CAM. Dai W, et al. Chemosphere. 2023 Jan;311(Pt 2):137119. doi: 10.1016/j.chemosphere.2022.137119. Epub 2022 Nov 2. Chemosphere. 2023. PMID: 36334742
The transcription of Heat Shock Protein 70 (HSP70) was significantly upregulated by heat shock but tended to reach the control levels after 42 h of recovery. The transcription of cytochrome P450 3A13 (CYP3A13) was upregulated 3-13 fold by PHE but suppressed by heat shock. …
The transcription of Heat Shock Protein 70 (HSP70) was significantly upregulated by heat shock but tended to reach the control levels after …
Cytochrome P-450 3A13 and endothelin jointly mediate ductus arteriosus constriction to oxygen in mice.
Baragatti B, Ciofini E, Scebba F, Angeloni D, Sodini D, Luin S, Ratto GM, Ottaviano V, Pagni E, Paolicchi A, Nencioni S, Coceani F. Baragatti B, et al. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H892-901. doi: 10.1152/ajpheart.00907.2010. Epub 2010 Dec 30. Am J Physiol Heart Circ Physiol. 2011. PMID: 21193583 Free article.
Here, we examined comparatively wild-type (WT) and CYP3A-null (Cyp3a(-/-)) mice for direct validation of this concept. We found that the CYP3A subfamily is represented only by CYP3A13 in the WT DA. CYP3A13 was also detected in the DA by immunofluorescence microscopy …
Here, we examined comparatively wild-type (WT) and CYP3A-null (Cyp3a(-/-)) mice for direct validation of this concept. We found that the CYP …
Aflatoxin B1 metabolism: Regulation by phase I and II metabolizing enzymes and chemoprotective agents.
Deng J, Zhao L, Zhang NY, Karrow NA, Krumm CS, Qi DS, Sun LH. Deng J, et al. Mutat Res Rev Mutat Res. 2018 Oct-Dec;778:79-89. doi: 10.1016/j.mrrev.2018.10.002. Epub 2018 Oct 29. Mutat Res Rev Mutat Res. 2018. PMID: 30454686 Review.
In humans, cytochrome P450 (CYP) 1A2, CYP3A4, CYP3A5, and CYP3A7 in liver and CYP2A13 in lung are essential for the bioactivation of AFB(1) to the extremely toxic exo-AFB(1)-8,9-epoxide (AFBO), whereas CYP1A1, CYP1A2, CYP2A6, and CYP3A4 are important in the turkey and duck, CYP1A …
In humans, cytochrome P450 (CYP) 1A2, CYP3A4, CYP3A5, and CYP3A7 in liver and CYP2A13 in lung are essential for the bioactivation of AFB(1) …
Mouse cytochrome P450 (Cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1.
Yanagimoto T, Itoh S, Sawada M, Kamataki T. Yanagimoto T, et al. Arch Biochem Biophys. 1997 Apr 15;340(2):215-8. doi: 10.1006/abbi.1997.9900. Arch Biochem Biophys. 1997. PMID: 9143324
S1 mapping analysis for the expression of Cyp3a11 and Cyp3a13 indicated that Cyp3a11 mRNA is predominantly expressed in mouse liver, compared with that of Cyp3a13. In addition, all of six inducers, such as dexamethasone, 3-methylcholanthrene, phenobarbital, polychlo …
S1 mapping analysis for the expression of Cyp3a11 and Cyp3a13 indicated that Cyp3a11 mRNA is predominantly expressed in mouse liver, …
In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.
Komura H, Iwaki M. Komura H, et al. Drug Metab Rev. 2011 Nov;43(4):476-98. doi: 10.3109/03602532.2011.597401. Epub 2011 Aug 23. Drug Metab Rev. 2011. PMID: 21859377 Review.
Based on mRNA expression levels, the major intestinal CYP3A isoform is CYP3A4 for humans, CYP3A4 (3A8) for monkeys, CYP3A9 for rats, cyp3a13 for mice, and CYP3A12 for dogs. Additionally, the intestinal-specific UGT would be UGT1A10 for humans, UGT1A8 for monkeys, and UGT1A …
Based on mRNA expression levels, the major intestinal CYP3A isoform is CYP3A4 for humans, CYP3A4 (3A8) for monkeys, CYP3A9 for rats, cyp3 …
45 results