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Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.
Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M. Bigley V, et al. Among authors: cytlak u. J Allergy Clin Immunol. 2018 Jun;141(6):2234-2248. doi: 10.1016/j.jaci.2017.08.044. Epub 2017 Nov 8. J Allergy Clin Immunol. 2018. PMID: 29128673 Free PMC article.
Human dendritic cell immunodeficiencies.
Bigley V, Cytlak U, Collin M. Bigley V, et al. Among authors: cytlak u. Semin Cell Dev Biol. 2019 Feb;86:50-61. doi: 10.1016/j.semcdb.2018.02.020. Epub 2018 Feb 23. Semin Cell Dev Biol. 2019. PMID: 29452225 Review.
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.
Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, McDonald D, Hulme G, Filby A, Carpenter B, Queen R, Hambleton S, Hague R, Lango Allen H, Thaventhiran JED, Doody G, Collin M, Bigley V. Cytlak U, et al. Immunity. 2020 Aug 18;53(2):353-370.e8. doi: 10.1016/j.immuni.2020.07.003. Epub 2020 Jul 30. Immunity. 2020. PMID: 32735845 Free PMC article.
Ikaros family zinc finger 1 regulates dendritic cell development and function in humans.
Cytlak U, Resteu A, Bogaert D, Kuehn HS, Altmann T, Gennery A, Jackson G, Kumanovics A, Voelkerding KV, Prader S, Dullaers M, Reichenbach J, Hill H, Haerynck F, Rosenzweig SD, Collin M, Bigley V. Cytlak U, et al. Nat Commun. 2018 Mar 27;9(1):1239. doi: 10.1038/s41467-018-02977-8. Nat Commun. 2018. PMID: 29588478 Free PMC article.
Donor monocyte-derived macrophages promote human acute graft-versus-host disease.
Jardine L, Cytlak U, Gunawan M, Reynolds G, Green K, Wang XN, Pagan S, Paramitha M, Lamb CA, Long AK, Hurst E, Nair S, Jackson GH, Publicover A, Bigley V, Haniffa M, Simpson AJ, Collin M. Jardine L, et al. Among authors: cytlak u. J Clin Invest. 2020 Sep 1;130(9):4574-4586. doi: 10.1172/JCI133909. J Clin Invest. 2020. PMID: 32453711 Free PMC article.
A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.
Bogaert DJ, Kuehn HS, Bonroy C, Calvo KR, Dehoorne J, Vanlander AV, De Bruyne M, Cytlak U, Bigley V, De Baets F, De Baere E, Rosenzweig SD, Haerynck F, Dullaers M. Bogaert DJ, et al. Among authors: cytlak u. J Allergy Clin Immunol. 2018 Jan;141(1):432-435.e7. doi: 10.1016/j.jaci.2017.08.019. Epub 2017 Sep 18. J Allergy Clin Immunol. 2018. PMID: 28927821 Free PMC article. No abstract available.
15 results