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Anti-IL-2 treatment impairs the expansion of T(reg) cell population during acute malaria and enhances the Th1 cell response at the chronic disease.
Zago CA, Bortoluci KR, Sardinha LR, Pretel FD, Castillo-Méndez SI, Freitas do Rosário AP, Hiyane MI, Muxel SM, Rodriguez-Málaga SM, Abrahamsohn IA, Álvarez JM, D'Império Lima MR. Zago CA, et al. PLoS One. 2012;7(1):e29894. doi: 10.1371/journal.pone.0029894. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272258 Free PMC article.
Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses.
Lage SL, Buzzo CL, Amaral EP, Matteucci KC, Massis LM, Icimoto MY, Carmona AK, D'Império Lima MR, Rodrigues MM, Ferreira LC, Amarante-Mendes GP, Bortoluci KR. Lage SL, et al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3321-30. doi: 10.1073/pnas.1305316110. Epub 2013 Aug 13. Proc Natl Acad Sci U S A. 2013. PMID: 23942123 Free PMC article.
Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Amaral EP, et al. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 24991816 Free PMC article.
Chagas disease: still many unsolved issues.
Álvarez JM, Fonseca R, Borges da Silva H, Marinho CR, Bortoluci KR, Sardinha LR, Epiphanio S, D'Império Lima MR. Álvarez JM, et al. Mediators Inflamm. 2014;2014:912965. doi: 10.1155/2014/912965. Epub 2014 Jun 29. Mediators Inflamm. 2014. PMID: 25104883 Free PMC article. Review.
In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria.
Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE. Borges da Silva H, et al. PLoS Pathog. 2015 Feb 6;11(2):e1004598. doi: 10.1371/journal.ppat.1004598. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25658925 Free PMC article.
P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria.
Salles ÉM, Menezes MN, Siqueira R, Borges da Silva H, Amaral EP, Castillo-Méndez SI, Cunha I, Cassado ADA, Vieira FS, Olivieri DN, Tadokoro CE, Alvarez JM, Coutinho-Silva R, D'Império-Lima MR. Salles ÉM, et al. PLoS Pathog. 2017 Aug 31;13(8):e1006595. doi: 10.1371/journal.ppat.1006595. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28859168 Free PMC article.
68 results