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High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models.
Xue L, Hamilton AG, Zhao G, Xiao Z, El-Mayta R, Han X, Gong N, Xiong X, Xu J, Figueroa-Espada CG, Shepherd SJ, Mukalel AJ, Alameh MG, Cui J, Wang K, Vaughan AE, Weissman D, Mitchell MJ. Xue L, et al. Nat Commun. 2024 Feb 29;15(1):1884. doi: 10.1038/s41467-024-45422-9. Nat Commun. 2024. PMID: 38424061 Free PMC article.
Emerging strategies for nanomedicine in autoimmunity.
Thatte AS, Billingsley MM, Weissman D, Melamed JR, Mitchell MJ. Thatte AS, et al. Adv Drug Deliv Rev. 2024 Apr;207:115194. doi: 10.1016/j.addr.2024.115194. Epub 2024 Feb 10. Adv Drug Deliv Rev. 2024. PMID: 38342243 Review.
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Flowers AJ, Gimotty PA, Xiao M, Mills G, Herlyn M, Dong H, Mitchell MJ, Kim J, Xu X, Guo W. Zhong W, et al. Cell Rep. 2023 Oct 31;42(10):113224. doi: 10.1016/j.celrep.2023.113224. Epub 2023 Oct 8. Cell Rep. 2023. PMID: 37805922 Free PMC article.
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines.
Shepherd SJ, Han X, Mukalel AJ, El-Mayta R, Thatte AS, Wu J, Padilla MS, Alameh MG, Srikumar N, Lee D, Weissman D, Issadore D, Mitchell MJ. Shepherd SJ, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303567120. doi: 10.1073/pnas.2303567120. Epub 2023 Aug 9. Proc Natl Acad Sci U S A. 2023. PMID: 37556502 Free PMC article.
46 results