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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
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2007 1
2008 1
2010 1
2011 1
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2013 1
2014 3
2015 3
2016 1
2017 1
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2019 2
2020 2
2021 3
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2023 2
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29 results

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Page 1
DPPA2, DPPA4, and other DPPA factor epigenomic functions in cell fate and cancer.
Klein RH, Knoepfler PS. Klein RH, et al. Stem Cell Reports. 2021 Dec 14;16(12):2844-2851. doi: 10.1016/j.stemcr.2021.10.008. Epub 2021 Nov 11. Stem Cell Reports. 2021. PMID: 34767751 Free PMC article. Review.
Many gene networks are shared between pluripotent stem cells and cancer; a concept exemplified by several DPPA factors such as DPPA2 and DPPA4, which are highly and selectively expressed in stem cells but also found to be reactivated in cancer. ...These findi …
Many gene networks are shared between pluripotent stem cells and cancer; a concept exemplified by several DPPA factors such as DPPA2 …
Dynamic cytosolic foci of DPPA4 in human pluripotent stem cells.
Abu-Dawud R, Mistry BV, Almahdali R, Matin MM, Alaiya A, Alghamdi F, Alamari H, Al-Yacoub N, Kashir J, Houssein M, Alawad A, Andrews PW, Assiri AM. Abu-Dawud R, et al. Tissue Cell. 2022 Oct;78:101893. doi: 10.1016/j.tice.2022.101893. Epub 2022 Aug 9. Tissue Cell. 2022. PMID: 36007377 Free article.
DPPA4 is localized in the nucleus, where it is associated with active chromatin. ...Co-immunoprecipitation studies highlighted novel protein interactors, many of which are also found in the cytosol and are implicated in mRNA processing and RNA and protein transport between …
DPPA4 is localized in the nucleus, where it is associated with active chromatin. ...Co-immunoprecipitation studies highlighted novel …
Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer.
Klein RH, Tung PY, Somanath P, Fehling HJ, Knoepfler PS. Klein RH, et al. Stem Cell Res. 2018 Aug;31:83-94. doi: 10.1016/j.scr.2018.07.009. Epub 2018 Jul 19. Stem Cell Res. 2018. PMID: 30031967 Free PMC article.
Developmental pluripotency associated factor 4 (Dppa4) is a highly specific marker of pluripotent cells, and is also overexpressed in certain cancers, but its function in either of these contexts is poorly understood. In this study, we use ChIP-Seq to identify Dp …
Developmental pluripotency associated factor 4 (Dppa4) is a highly specific marker of pluripotent cells, and is also overexpressed in …
The expressions of stem cell markers: Oct4, Nanog, Sox2, nucleostemin, Bmi, Zfx, Tcl1, Tbx3, Dppa4, and Esrrb in bladder, colon, and prostate cancer, and certain cancer cell lines.
Amini S, Fathi F, Mobalegi J, Sofimajidpour H, Ghadimi T. Amini S, et al. Anat Cell Biol. 2014 Mar;47(1):1-11. doi: 10.5115/acb.2014.47.1.1. Epub 2014 Mar 13. Anat Cell Biol. 2014. PMID: 24693477 Free PMC article.
Expressions of stem cell specific marker genes were detected in all examined cancer cell lines, in 40% to 100% of bladder cancer samples, and in 60% to 100% of colon and prostate cancer samples. ...Our data show that stem cell markers Oct4, Nanog, Sox2, nucle …
Expressions of stem cell specific marker genes were detected in all examined cancer cell lines, in 40% to 100% of bladder cancer …
High developmental pluripotency-associated 4 expression promotes cell proliferation and glycolysis, and predicts poor prognosis in non-small-cell lung cancer.
Li L, Wang Y, Wang Q, Qu J, Wei X, Xu J, Wang Y, Suo F, Zhang Y. Li L, et al. Mol Med Rep. 2019 Jul;20(1):445-454. doi: 10.3892/mmr.2019.10272. Epub 2019 May 22. Mol Med Rep. 2019. PMID: 31180527 Free PMC article.
The developmental pluripotency-associated 4 (Dppa4) gene serves critical roles in cell self-renewal, as well as in cancer development and progression. However, the regulatory role of Dppa4 in non-small-cell lung cancer (NSCLC) and its underlying mechan …
The developmental pluripotency-associated 4 (Dppa4) gene serves critical roles in cell self-renewal, as well as in cancer deve …
Targeting glycolysis in non-small cell lung cancer: Promises and challenges.
Xu JQ, Fu YL, Zhang J, Zhang KY, Ma J, Tang JY, Zhang ZW, Zhou ZY. Xu JQ, et al. Front Pharmacol. 2022 Nov 30;13:1037341. doi: 10.3389/fphar.2022.1037341. eCollection 2022. Front Pharmacol. 2022. PMID: 36532721 Free PMC article. Review.
Metabolic disturbance, particularly of glucose metabolism, is a hallmark of tumors such as non-small cell lung cancer (NSCLC). Cancer cells tend to reprogram a majority of glucose metabolism reactions into glycolysis, even in oxygen-rich environments. ...However, LD …
Metabolic disturbance, particularly of glucose metabolism, is a hallmark of tumors such as non-small cell lung cancer (NSCLC). Can …
Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer.
Zhang M, Cui F, Lu S, Lu H, Xue Y, Wang J, Chen J, Zhao S, Ma S, Zhang Y, Yu Y, Peng Z, Tang H. Zhang M, et al. J Exp Clin Cancer Res. 2015 Jun 11;34(1):60. doi: 10.1186/s13046-015-0176-z. J Exp Clin Cancer Res. 2015. PMID: 26063247 Free PMC article.
The present study investigates the expression and clinical significance of Dppa4 in colon cancer. METHODS: Real-time polymerase chain reaction and Western blotting were used to evaluate Dppa4 mRNA and protein expression in 39 pairs of fresh-frozzen colon c …
The present study investigates the expression and clinical significance of Dppa4 in colon cancer. METHODS: Real-time polymeras …
Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.
Tung PY, Varlakhanova NV, Knoepfler PS. Tung PY, et al. Stem Cells. 2013 Nov;31(11):2330-42. doi: 10.1002/stem.1526. Stem Cells. 2013. PMID: 23963736 Free PMC article.
DPPA4 has not been previously identified as an oncogene but is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. DPPA4 is also mutated in some cancers. In direct transformation assays, we validated that DPPA4 …
DPPA4 has not been previously identified as an oncogene but is highly expressed in embryonal carcinomas, pluripotent germ cell tumors …
Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types.
Naderi E, Aguado-Barrera ME, Schack LMH, Dorling L, Rattay T, Fachal L, Summersgill H, Martínez-Calvo L, Welsh C, Dudding T, Odding Y, Varela-Pazos A, Jena R, Thomson DJ, Steenbakkers RJHM, Dennis J, Lobato-Busto R, Alsner J, Ness A, Nutting C, Gómez-Caamaño A, Eriksen JG, Thomas SJ, Bates AM, Webb AJ, Choudhury A, Rosenstein BS, Taboada-Valladares B, Herskind C, Azria D, Dearnaley DP, de Ruysscher D, Sperk E, Hall E, Stobart H, Chang-Claude J, De Ruyck K, Veldeman L, Altabas M, De Santis MC, Farcy-Jacquet MP, Veldwijk MR, Sydes MR, Parliament M, Usmani N, Burnet NG, Seibold P, Symonds RP, Elliott RM, Bultijnck R, Gutiérrez-Enríquez S, Mollà M, Gulliford SL, Green S, Rancati T, Reyes V, Carballo A, Peleteiro P, Sosa-Fajardo P, Parker C, Fonteyne V, Johnson K, Lambrecht M, Vanneste B, Valdagni R, Giraldo A, Ramos M, Diergaarde B, Liu G, Leal SM, Chua MLK, Pring M, Overgaard J, Cascallar-Caneda LM, Duprez F, Talbot CJ, Barnett GC, Dunning AM, Vega A, Andreassen CN, Langendijk JA, West CML, Alizadeh BZ, Kerns SL; Radiogenomics Consortium. Naderi E, et al. JNCI Cancer Spectr. 2023 Oct 31;7(6):pkad088. doi: 10.1093/jncics/pkad088. JNCI Cancer Spectr. 2023. PMID: 37862240 Free PMC article.
Linkage disequilibrium score regression estimated shared single-nucleotide variation (SNV-formerly SNP)-based heritability of rSTATacute in all patients and for each cancer type. RESULTS: Shared SNV-based heritability of STATacute among all cancer types was estimate …
Linkage disequilibrium score regression estimated shared single-nucleotide variation (SNV-formerly SNP)-based heritability of rSTATacute in …
29 results