Dai X - Search Results

1

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W. Wang B, et al. Among authors: dai x. Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10. Nature. 2017. PMID: 28489822 Free PMC article.

2

AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.

Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W. Guo J, et al. Among authors: dai x. Nat Cell Biol. 2019 Feb;21(2):226-237. doi: 10.1038/s41556-018-0261-6. Epub 2019 Jan 28. Nat Cell Biol. 2019. PMID: 30692625 Free PMC article.

3

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.

Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, Asara JM, Pandolfi PP, Yang Y, He Z, Gao G, Wei W. Gan W, et al. Among authors: dai x. Nat Cell Biol. 2020 Feb;22(2):246-256. doi: 10.1038/s41556-020-0463-6. Epub 2020 Feb 3. Nat Cell Biol. 2020. PMID: 32015438 Free PMC article.

4

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Among authors: dai x. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

5

Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells.

Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, Hu G, Guo J. Zhang L, et al. Among authors: dai x. Cancer Lett. 2017 Apr 1;390:11-20. doi: 10.1016/j.canlet.2017.01.003. Epub 2017 Jan 13. Cancer Lett. 2017. PMID: 28089830 Free PMC article.

6

Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6.

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, North BJ, Huo J, Zhang J. Tan Y, et al. Among authors: dai x. Oncotarget. 2017 Jul 18;8(29):47890-47901. doi: 10.18632/oncotarget.18141. Oncotarget. 2017. PMID: 28599312 Free PMC article.

7

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, Buckley DL, Qi J, Buser L, Liu P, Inuzuka H, Beck AH, Wang L, Wild PJ, Garraway LA, Rubin MA, Barbieri CE, Wong KK, Muthuswamy SK, Huang J, Chen Y, Bradner JE, Wei W. Dai X, et al. Nat Med. 2017 Sep;23(9):1063-1071. doi: 10.1038/nm.4378. Epub 2017 Aug 14. Nat Med. 2017. PMID: 28805820 Free PMC article.

8

Functional analysis of Cullin 3 E3 ligases in tumorigenesis.

Cheng J, Guo J, Wang Z, North BJ, Tao K, Dai X, Wei W. Cheng J, et al. Among authors: dai x. Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):11-28. doi: 10.1016/j.bbcan.2017.11.001. Epub 2017 Nov 8. Biochim Biophys Acta Rev Cancer. 2018. PMID: 29128526 Free PMC article. Review.

9

Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: dai x. Nature. 2018 Jan 4;553(7686):91-95. doi: 10.1038/nature25015. Epub 2017 Nov 16. Nature. 2018. PMID: 29160310 Free PMC article.

10

The emerging roles of protein homeostasis-governing pathways in Alzheimer's disease.

Cheng J, North BJ, Zhang T, Dai X, Tao K, Guo J, Wei W. Cheng J, et al. Among authors: dai x. Aging Cell. 2018 Oct;17(5):e12801. doi: 10.1111/acel.12801. Epub 2018 Jul 10. Aging Cell. 2018. PMID: 29992725 Free PMC article. Review.

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