Darwish KM - Search Results

1

Repurposing of Sitagliptin- Melittin Optimized Nanoformula against SARS-CoV-2: Antiviral Screening and Molecular Docking Studies.

Al-Rabia MW, Alhakamy NA, Ahmed OAA, Eljaaly K, Alaofi AL, Mostafa A, Asfour HZ, Aldarmahi AA, Darwish KM, Ibrahim TS, Fahmy UA. Al-Rabia MW, et al. Among authors: darwish km. Pharmaceutics. 2021 Feb 26;13(3):307. doi: 10.3390/pharmaceutics13030307. Pharmaceutics. 2021. PMID: 33652894 Free PMC article.

2

The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme.

Malebari AM, Ibrahim TS, Salem IM, Salama I, Khayyat AN, Mostafa SM, El-Sabbagh OI, Darwish KM. Malebari AM, et al. Among authors: darwish km. Pharmaceuticals (Basel). 2020 Sep 18;13(9):252. doi: 10.3390/ph13090252. Pharmaceuticals (Basel). 2020. PMID: 32961906 Free PMC article.

3

Repurposing α-Adrenoreceptor Blockers as Promising Anti-Virulence Agents in Gram-Negative Bacteria.

Almalki AJ, Ibrahim TS, Elhady SS, Darwish KM, Hegazy WAH. Almalki AJ, et al. Among authors: darwish km. Antibiotics (Basel). 2022 Jan 29;11(2):178. doi: 10.3390/antibiotics11020178. Antibiotics (Basel). 2022. PMID: 35203781 Free PMC article.

4

Computational and Biological Evaluation of β-Adrenoreceptor Blockers as Promising Bacterial Anti-Virulence Agents.

Almalki AJ, Ibrahim TS, Elhady SS, Hegazy WAH, Darwish KM. Almalki AJ, et al. Among authors: darwish km. Pharmaceuticals (Basel). 2022 Jan 18;15(2):110. doi: 10.3390/ph15020110. Pharmaceuticals (Basel). 2022. PMID: 35215223 Free PMC article.

5

β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: rational based design, in silico, in vitro, and SAR studies for lead optimization.

Hamed MIA, Darwish KM, Soltane R, Chrouda A, Mostafa A, Abo Shama NM, Elhady SS, Abulkhair HS, Khodir AE, Elmaaty AA, Al-Karmalawy AA. Hamed MIA, et al. Among authors: darwish km. RSC Adv. 2021 Nov 3;11(56):35536-35558. doi: 10.1039/d1ra04820a. eCollection 2021 Oct 28. RSC Adv. 2021. PMID: 35493159 Free PMC article.

6

Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus.

Khayat MT, Abbas HA, Ibrahim TS, Khayyat AN, Alharbi M, Darwish KM, Elhady SS, Khafagy ES, Safo MK, Hegazy WAH. Khayat MT, et al. Among authors: darwish km. Biomedicines. 2022 May 18;10(5):1169. doi: 10.3390/biomedicines10051169. Biomedicines. 2022. PMID: 35625906 Free PMC article.

7

Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis.

Khayat MT, Ibrahim TS, Darwish KM, Khayyat AN, Alharbi M, Khafagy ES, Ali MAM, Hegazy WAH, Abbas HA. Khayat MT, et al. Among authors: darwish km. Microorganisms. 2022 Dec 12;10(12):2455. doi: 10.3390/microorganisms10122455. Microorganisms. 2022. PMID: 36557708 Free PMC article.

8

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor.

Al-Karmalawy AA, Dahab MA, Metwaly AM, Elhady SS, Elkaeed EB, Eissa IH, Darwish KM. Al-Karmalawy AA, et al. Among authors: darwish km. Front Chem. 2021 May 4;9:661230. doi: 10.3389/fchem.2021.661230. eCollection 2021. Front Chem. 2021. PMID: 34017819 Free PMC article.

9

Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies.

Zaki AA, Ashour A, Elhady SS, Darwish KM, Al-Karmalawy AA. Zaki AA, et al. Among authors: darwish km. J Tradit Complement Med. 2022 Jan;12(1):16-34. doi: 10.1016/j.jtcme.2021.05.001. Epub 2021 May 17. J Tradit Complement Med. 2022. PMID: 34026584 Free PMC article.

10

Molecular Docking and Dynamics Simulation Study of Hyrtios erectus Isolated Scalarane Sesterterpenes as Potential SARS-CoV-2 Dual Target Inhibitors.

Elhady SS, Abdelhameed RFA, Malatani RT, Alahdal AM, Bogari HA, Almalki AJ, Mohammad KA, Ahmed SA, Khedr AIM, Darwish KM. Elhady SS, et al. Among authors: darwish km. Biology (Basel). 2021 May 1;10(5):389. doi: 10.3390/biology10050389. Biology (Basel). 2021. PMID: 34062724 Free PMC article.

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