David SA - Search Results

1

Lysine-spermine conjugates: hydrophobic polyamine amides as potent lipopolysaccharide sequestrants.

Burns MR, Wood SJ, Miller KA, Nguyen T, Cromer JR, David SA. Burns MR, et al. Among authors: david sa. Bioorg Med Chem. 2005 Apr 1;13(7):2523-36. doi: 10.1016/j.bmc.2005.01.038. Bioorg Med Chem. 2005. PMID: 15755654

2

Functionalized dendrimers as endotoxin sponges.

Cromer JR, Wood SJ, Miller KA, Nguyen T, David SA. Cromer JR, et al. Among authors: david sa. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1295-8. doi: 10.1016/j.bmcl.2005.01.026. Bioorg Med Chem Lett. 2005. PMID: 15713373

3

Lipopolysaccharide sequestrants: structural correlates of activity and toxicity in novel acylhomospermines.

Miller KA, Suresh Kumar EV, Wood SJ, Cromer JR, Datta A, David SA. Miller KA, et al. Among authors: david sa. J Med Chem. 2005 Apr 7;48(7):2589-99. doi: 10.1021/jm049449j. J Med Chem. 2005. PMID: 15801849 Free PMC article.

4

Structure-activity relationships in lipopolysaccharide neutralizers: design, synthesis, and biological evaluation of a 540-membered amphipathic bisamide library.

Burns MR, Jenkins SA, Wood SJ, Miller K, David SA. Burns MR, et al. Among authors: david sa. J Comb Chem. 2006 Jan-Feb;8(1):32-43. doi: 10.1021/cc0500755. J Comb Chem. 2006. PMID: 16398551

5

Structural correlation between lipophilicity and lipopolysaccharide-sequestering activity in spermine-sulfonamide analogs.

Burns MR, Jenkins SA, Vermeulen NM, Balakrishna R, Nguyen TB, Kimbrell MR, David SA. Burns MR, et al. Among authors: david sa. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6209-12. doi: 10.1016/j.bmcl.2006.09.026. Epub 2006 Sep 28. Bioorg Med Chem Lett. 2006. PMID: 17010608 Free PMC article.

6

Polycationic sulfonamides for the sequestration of endotoxin.

Burns MR, Jenkins SA, Kimbrell MR, Balakrishna R, Nguyen TB, Abbo BG, David SA. Burns MR, et al. Among authors: david sa. J Med Chem. 2007 Feb 22;50(4):877-88. doi: 10.1021/jm061198m. Epub 2007 Jan 26. J Med Chem. 2007. PMID: 17256835

7

Novel endotoxin-sequestering compounds with terephthalaldehyde-bis-guanylhydrazone scaffolds.

Khownium K, Wood SJ, Miller KA, Balakrishna R, Nguyen TB, Kimbrell MR, Georg GI, David SA. Khownium K, et al. Among authors: david sa. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1305-8. doi: 10.1016/j.bmcl.2005.11.059. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377188

8

Anti-endotoxin agents. 2. Pilot high-throughput screening for novel lipopolysaccharide-recognizing motifs in small molecules.

Wood SJ, Miller KA, David SA. Wood SJ, et al. Among authors: david sa. Comb Chem High Throughput Screen. 2004 Dec;7(8):733-47. doi: 10.2174/1386207043328229. Comb Chem High Throughput Screen. 2004. PMID: 15578935 Free PMC article.

9

Molecular modeling analysis of the interaction of novel bis-cationic ligands with the lipid A moiety of lipopolysaccharide.

Guo JX, Wood SJ, David SA, Lushington GH. Guo JX, et al. Among authors: david sa. Bioorg Med Chem Lett. 2006 Feb;16(3):714-7. doi: 10.1016/j.bmcl.2005.10.025. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16266804

10

Anti-endotoxin agents. 3. Rapid identification of high-affinity lipopolysaccharide-binding compounds in a substituted polyamine library.

Wood SJ, Miller KA, Lushington GH, Burns MR, David SA. Wood SJ, et al. Among authors: david sa. Comb Chem High Throughput Screen. 2006 Jan;9(1):27-36. doi: 10.2174/138620706775213903. Comb Chem High Throughput Screen. 2006. PMID: 16454684

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