Davies PL - Search Results

1

Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics.

Low KE, Ler S, Chen KJ, Campbell RL, Hickey JL, Tan J, Scully CC, Davies PL, Yudin AK, Zaretsky S. Low KE, et al. Among authors: davies pl. J Med Chem. 2016 Jun 9;59(11):5403-15. doi: 10.1021/acs.jmedchem.6b00267. Epub 2016 May 18. J Med Chem. 2016. PMID: 27148623

2

Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.

Hosfield CM, Moldoveanu T, Davies PL, Elce JS, Jia Z. Hosfield CM, et al. Among authors: davies pl. J Biol Chem. 2001 Mar 9;276(10):7404-7. doi: 10.1074/jbc.M007352200. Epub 2000 Dec 1. J Biol Chem. 2001. PMID: 11102442 Free article.

3

Calpain activation by cooperative Ca2+ binding at two non-EF-hand sites.

Moldoveanu T, Jia Z, Davies PL. Moldoveanu T, et al. Among authors: davies pl. J Biol Chem. 2004 Feb 13;279(7):6106-14. doi: 10.1074/jbc.M310460200. Epub 2003 Oct 27. J Biol Chem. 2004. PMID: 14581465 Free article.

4

Insertion sequence 1 of muscle-specific calpain, p94, acts as an internal propeptide.

Diaz BG, Moldoveanu T, Kuiper MJ, Campbell RL, Davies PL. Diaz BG, et al. Among authors: davies pl. J Biol Chem. 2004 Jun 25;279(26):27656-66. doi: 10.1074/jbc.M313290200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073171 Free article.

5

Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.

Moldoveanu T, Campbell RL, Cuerrier D, Davies PL. Moldoveanu T, et al. Among authors: davies pl. J Mol Biol. 2004 Nov 5;343(5):1313-26. doi: 10.1016/j.jmb.2004.09.016. J Mol Biol. 2004. PMID: 15491615

6

Ritonavir does not inhibit calpain in vitro.

Cuerrier D, Nie Z, Badley AD, Davies PL. Cuerrier D, et al. Among authors: davies pl. Biochem Biophys Res Commun. 2005 Feb 4;327(1):208-11. doi: 10.1016/j.bbrc.2004.11.161. Biochem Biophys Res Commun. 2005. PMID: 15629450

7

Homodimerization of calpain 3 penta-EF-hand domain.

Ravulapalli R, Diaz BG, Campbell RL, Davies PL. Ravulapalli R, et al. Among authors: davies pl. Biochem J. 2005 Jun 1;388(Pt 2):585-91. doi: 10.1042/BJ20041821. Biochem J. 2005. PMID: 15660530 Free PMC article.

8

Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions.

Cuerrier D, Moldoveanu T, Davies PL. Cuerrier D, et al. Among authors: davies pl. J Biol Chem. 2005 Dec 9;280(49):40632-41. doi: 10.1074/jbc.M506870200. Epub 2005 Oct 10. J Biol Chem. 2005. PMID: 16216885 Free article.

9

Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography.

Cuerrier D, Moldoveanu T, Inoue J, Davies PL, Campbell RL. Cuerrier D, et al. Among authors: davies pl. Biochemistry. 2006 Jun 20;45(24):7446-52. doi: 10.1021/bi060425j. Biochemistry. 2006. PMID: 16768440

10

Structural modeling of snow flea antifreeze protein.

Lin FH, Graham LA, Campbell RL, Davies PL. Lin FH, et al. Among authors: davies pl. Biophys J. 2007 Mar 1;92(5):1717-23. doi: 10.1529/biophysj.106.093435. Epub 2006 Dec 8. Biophys J. 2007. PMID: 17158562 Free PMC article.

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