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Animal and Cellular Models of Alzheimer's Disease: Progress, Promise, and Future Approaches.
Trujillo-Estrada L, Sanchez-Mejias E, Sanchez-Varo R, Garcia-Leon JA, Nuñez-Diaz C, Davila JC, Vitorica J, LaFerla FM, Moreno-Gonzalez I, Gutierrez A, Baglietto-Vargas D. Trujillo-Estrada L, et al. Among authors: davila jc. Neuroscientist. 2022 Dec;28(6):572-593. doi: 10.1177/10738584211001753. Epub 2021 Mar 26. Neuroscientist. 2022. PMID: 33769131 Review.
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.
Sanchez-Varo R, Trujillo-Estrada L, Sanchez-Mejias E, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, De Castro V, Jimenez S, Ruano D, Vizuete M, Davila JC, Garcia-Verdugo JM, Jimenez AJ, Vitorica J, Gutierrez A. Sanchez-Varo R, et al. Among authors: davila jc. Acta Neuropathol. 2012 Jan;123(1):53-70. doi: 10.1007/s00401-011-0896-x. Epub 2011 Oct 22. Acta Neuropathol. 2012. PMID: 22020633 Free PMC article.
Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.
Torres M, Jimenez S, Sanchez-Varo R, Navarro V, Trujillo-Estrada L, Sanchez-Mejias E, Carmona I, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Torres M, et al. Among authors: davila jc. Mol Neurodegener. 2012 Nov 22;7:59. doi: 10.1186/1750-1326-7-59. Mol Neurodegener. 2012. PMID: 23173743 Free PMC article.
In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer's disease pathology.
Trujillo-Estrada L, Jimenez S, De Castro V, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, Navarro V, Sanchez-Varo R, Sanchez-Mejias E, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Trujillo-Estrada L, et al. Among authors: davila jc. Acta Neuropathol Commun. 2013 Nov 12;1:73. doi: 10.1186/2051-5960-1-73. Acta Neuropathol Commun. 2013. PMID: 24252759 Free PMC article.
Expression of Gls and Gls2 glutaminase isoforms in astrocytes.
Cardona C, Sánchez-Mejías E, Dávila JC, Martín-Rufián M, Campos-Sandoval JA, Vitorica J, Alonso FJ, Matés JM, Segura JA, Norenberg MD, Rama Rao KV, Jayakumar AR, Gutiérrez A, Márquez J. Cardona C, et al. Among authors: davila jc. Glia. 2015 Mar;63(3):365-82. doi: 10.1002/glia.22758. Epub 2014 Oct 9. Glia. 2015. PMID: 25297978
Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.
Sanchez-Mejias E, Navarro V, Jimenez S, Sanchez-Mico M, Sanchez-Varo R, Nuñez-Diaz C, Trujillo-Estrada L, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Sanchez-Mejias E, et al. Among authors: davila jc. Acta Neuropathol. 2016 Dec;132(6):897-916. doi: 10.1007/s00401-016-1630-5. Epub 2016 Oct 14. Acta Neuropathol. 2016. PMID: 27743026 Free PMC article.
N370S-GBA1 mutation causes lysosomal cholesterol accumulation in Parkinson's disease.
García-Sanz P, Orgaz L, Bueno-Gil G, Espadas I, Rodríguez-Traver E, Kulisevsky J, Gutierrez A, Dávila JC, González-Polo RA, Fuentes JM, Mir P, Vicario C, Moratalla R. García-Sanz P, et al. Among authors: davila jc. Mov Disord. 2017 Oct;32(10):1409-1422. doi: 10.1002/mds.27119. Epub 2017 Aug 5. Mov Disord. 2017. PMID: 28779532
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease.
Baglietto-Vargas D, Sánchez-Mejias E, Navarro V, Jimenez S, Trujillo-Estrada L, Gómez-Arboledas A, Sánchez-Mico M, Sánchez-Varo R, Vizuete M, Dávila JC, García-Verdugo JM, Vitorica J, Gutierrez A. Baglietto-Vargas D, et al. Among authors: davila jc. Sci Rep. 2017 Aug 30;7(1):10085. doi: 10.1038/s41598-017-10353-7. Sci Rep. 2017. PMID: 28855626 Free PMC article.
193 results