Davis TW - Search Results

1

Preclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design.

Kinsella TJ, Schupp JE, Davis TW, Berry SE, Hwang HS, Warren K, Balis F, Barnett J, Sands H. Kinsella TJ, et al. Among authors: davis tw. Clin Cancer Res. 2000 Sep;6(9):3670-9. Clin Cancer Res. 2000. PMID: 10999760

2

Radiosensitivity of thymidylate synthase-deficient human tumor cells is affected by progression through the G1 restriction point into S-phase: implications for fluoropyrimidine radiosensitization.

Hwang HS, Davis TW, Houghton JA, Kinsella TJ. Hwang HS, et al. Among authors: davis tw. Cancer Res. 2000 Jan 1;60(1):92-100. Cancer Res. 2000. PMID: 10646859

3

Preclinical toxicity and efficacy study of a 14-day schedule of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as a prodrug for 5-iodo-2'-deoxyuridine radiosensitization in U251 human glioblastoma xenografts.

Kinsella TJ, Vielhuber KA, Kunugi KA, Schupp J, Davis TW, Sands H. Kinsella TJ, et al. Among authors: davis tw. Clin Cancer Res. 2000 Apr;6(4):1468-75. Clin Cancer Res. 2000. PMID: 10778979

4

Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine.

Berry SE, Davis TW, Schupp JE, Hwang HS, de Wind N, Kinsella TJ. Berry SE, et al. Among authors: davis tw. Cancer Res. 2000 Oct 15;60(20):5773-80. Cancer Res. 2000. PMID: 11059773

5

The mismatch repair protein, hMLH1, mediates 5-substituted halogenated thymidine analogue cytotoxicity, DNA incorporation, and radiosensitization in human colon cancer cells.

Berry SE, Garces C, Hwang HS, Kunugi K, Meyers M, Davis TW, Boothman DA, Kinsella TJ. Berry SE, et al. Among authors: davis tw. Cancer Res. 1999 Apr 15;59(8):1840-5. Cancer Res. 1999. PMID: 10213489

6

Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation.

Davis TW, Wilson-Van Patten C, Meyers M, Kunugi KA, Cuthill S, Reznikoff C, Garces C, Boland CR, Kinsella TJ, Fishel R, Boothman DA. Davis TW, et al. Cancer Res. 1998 Feb 15;58(4):767-78. Cancer Res. 1998. PMID: 9485033

7

Damage-sensing mechanisms in human cells after ionizing radiation.

Boothman DA, Burrows HL, Yang CR, Davis TW, Wuerzberger SM, Planchon SM, Odegaard E, Lewis JE, Pink J, Meyers M, Patten CW, Sharda N, Kinsella TJ. Boothman DA, et al. Among authors: davis tw. Stem Cells. 1997;15 Suppl 2:27-42. doi: 10.1002/stem.5530150707. Stem Cells. 1997. PMID: 9368284

8

Coordinate modulation of Sp1, NF-kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation.

Yang CR, Wilson-Van Patten C, Planchon SM, Wuerzberger-Davis SM, Davis TW, Cuthill S, Miyamoto S, Boothman DA. Yang CR, et al. Among authors: davis tw. FASEB J. 2000 Feb;14(2):379-90. doi: 10.1096/fasebj.14.2.379. FASEB J. 2000. PMID: 10657994

9

Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors.

Zweifel BS, Davis TW, Ornberg RL, Masferrer JL. Zweifel BS, et al. Among authors: davis tw. Cancer Res. 2002 Nov 15;62(22):6706-11. Cancer Res. 2002. PMID: 12438270

10

Cell cycle regulation of the human DNA mismatch repair genes hMSH2, hMLH1, and hPMS2.

Meyers M, Theodosiou M, Acharya S, Odegaard E, Wilson T, Lewis JE, Davis TW, Wilson-Van Patten C, Fishel R, Boothman DA. Meyers M, et al. Among authors: davis tw. Cancer Res. 1997 Jan 15;57(2):206-8. Cancer Res. 1997. PMID: 9000555

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