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Integrative radiogenomic analysis for multicentric radiophenotype in glioblastoma.
Kong DS, Kim J, Lee IH, Kim ST, Seol HJ, Lee JI, Park WY, Ryu G, Wang Z, Ma'ayan A, Nam DH. Kong DS, et al. Oncotarget. 2016 Mar 8;7(10):11526-38. doi: 10.18632/oncotarget.7115. Oncotarget. 2016. PMID: 26863628 Free PMC article.
Integration of the CNV and expression datasets identified twelve representative genes: CPM, LANCL2, LAMP1, GAS6, DCUN1D2, CDK4, AGAP2, TSPAN33, PDLIM1, CLDN12, and GTPBP10 having high correlation across CNV, gene expression and patient outcome. ...
Integration of the CNV and expression datasets identified twelve representative genes: CPM, LANCL2, LAMP1, GAS6, DCUN1D2, CDK4, AGAP2 …
Concentration of neddylation-related molecules in paranodal myelin of the peripheral nervous system.
Kajigaya H, Ishibashi T, Hayashi A, Yamaguchi Y, Baba H. Kajigaya H, et al. Proc Jpn Acad Ser B Phys Biol Sci. 2016;92(2):56-68. doi: 10.2183/pjab.92.56. Proc Jpn Acad Ser B Phys Biol Sci. 2016. PMID: 26860454 Free PMC article.
In this study, we demonstrate that neddylation-related molecules, NEDD8 and DCUN1D2 (defective in cullin neddylation 1, domain containing 2), were concentrated at the paranode of peripheral myelin, in addition to the myelinated and unmyelinated Schwann cell bodies. ...
In this study, we demonstrate that neddylation-related molecules, NEDD8 and DCUN1D2 (defective in cullin neddylation 1, domain contai …
Whole-genome sequencing reveals breed-differential CNVs between Tongcheng and Large White pigs.
Wu Q †, Zhou Y †, Wang Y, Zhang Y, Shen Y, Su Q, Gao G, Xu H, Zhou X, Liu B. Wu Q †, et al. Anim Genet. 2020 Dec;51(6):940-944. doi: 10.1111/age.12993. Epub 2020 Aug 17. Anim Genet. 2020. PMID: 32808316
Using a systematic analysis of the genome and transcriptome data, we further identified four novel breed-differential CNVs on the functional genes (disease-resistant, DCUN1D2 and SPARCL1; lipid metabolism, PLEKHA2 and SLCO1A2). Subsequent PCR validation confirmed their acc …
Using a systematic analysis of the genome and transcriptome data, we further identified four novel breed-differential CNVs on the functional …
Circuit-wide proteomics profiling reveals brain region-specific protein signatures in the male WKY rats with endogenous depression.
Liao J, Mi X, Zeng G, Wei Y, Dai X, Ye Q, Chen X, Zhang J. Liao J, et al. J Affect Disord. 2023 Jan 1;320:98-107. doi: 10.1016/j.jad.2022.09.086. Epub 2022 Sep 23. J Affect Disord. 2023. PMID: 36162674
A cerebral regional commonality and specificity were evident in the signaling pathways enriched in the WKY model, and a total of 15 brain region-specific DEPs were identified to closely correlate with the depression-like phenotypes (in the mPFC: Lrrc8d, Dcun1d2, and Mtnd5; …
A cerebral regional commonality and specificity were evident in the signaling pathways enriched in the WKY model, and a total of 15 brain re …
Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.
Sánchez-Abarca LI, Gutierrez-Cosio S, Santamaría C, Caballero-Velazquez T, Blanco B, Herrero-Sánchez C, García JL, Carrancio S, Hernández-Campo P, González FJ, Flores T, Ciudad L, Ballestar E, Del Cañizo C, San Miguel JF, Pérez-Simon JA. Sánchez-Abarca LI, et al. Blood. 2010 Jan 7;115(1):107-21. doi: 10.1182/blood-2009-03-210393. Epub 2009 Nov 3. Blood. 2010. PMID: 19887673 Free article.
This effect was not attributable to a proapoptotic effect of the drug but to the down-regulation of genes involved in T-cell cycle progression and activation such as CCNG2, MTCP1, CD58, and ADK and up-regulation of genes that induce cell-growth arrest, such as DCUN1D2, U2A …
This effect was not attributable to a proapoptotic effect of the drug but to the down-regulation of genes involved in T-cell cycle progressi …
Dystonia, facial dysmorphism, intellectual disability and breast cancer associated with a chromosome 13q34 duplication and overexpression of TFDP1: case report.
Moscovich M, LeDoux MS, Xiao J, Rampon GL, Vemula SR, Rodriguez RL, Foote KD, Okun MS. Moscovich M, et al. BMC Med Genet. 2013 Jul 13;14:70. doi: 10.1186/1471-2350-14-70. BMC Med Genet. 2013. PMID: 23849371 Free PMC article.
Genomic breakpoint analysis, quantitative PCR (qPCR) and leukocyte gene expression were used to characterize the structural variant. The 218,345 bp duplication was found to include ADPRHL1, DCUN1D2, and TMCO3, and a 69 bp fragment from a long terminal repeat (LTR) located …
Genomic breakpoint analysis, quantitative PCR (qPCR) and leukocyte gene expression were used to characterize the structural variant. The 218 …