De La Roche M - Search Results

1

A cell-engineered system to assess tumor cell sensitivity to CD8⁺ T cell-mediated cytotoxicity.

Nelson N, Lopez-Pelaez M, Palazon A, Poon E, De La Roche M, Barry S, Valge-Archer V, Wilkinson RW, Dovedi SJ, Smith PD. Nelson N, et al. Among authors: de la roche m. Oncoimmunology. 2019 Apr 26;8(8):1599635. doi: 10.1080/2162402X.2019.1599635. eCollection 2019. Oncoimmunology. 2019. PMID: 31413906 Free PMC article.

2

Hedgehog signalling in CD4⁺ T helper cell polarisation.

Hanna J, de la Roche M. Hanna J, et al. Among authors: de la roche m. Int J Biochem Cell Biol. 2024 Mar;168:106518. doi: 10.1016/j.biocel.2024.106518. Epub 2024 Jan 11. Int J Biochem Cell Biol. 2024. PMID: 38216086 Free article. Review.

3

A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo.

Cassidy LD, Young AR, Pérez-Mancera PA, Nimmervoll B, Jaulim A, Chen HC, McIntyre DJO, Brais R, Ricketts T, Pacey S, De La Roche M, Gilbertson RJ, Rubinsztein DC, Narita M. Cassidy LD, et al. Among authors: de la roche m. Autophagy. 2018;14(7):1256-1266. doi: 10.1080/15548627.2018.1458172. Epub 2018 Jul 12. Autophagy. 2018. PMID: 29999454 Free PMC article.

4

Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules.

Ilca FT, Neerincx A, Wills MR, de la Roche M, Boyle LH. Ilca FT, et al. Among authors: de la roche m. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9353-E9361. doi: 10.1073/pnas.1809465115. Epub 2018 Sep 13. Proc Natl Acad Sci U S A. 2018. PMID: 30213851 Free PMC article.

5

Centrosome docking at the immunological synapse is controlled by Lck signaling.

Tsun A, Qureshi I, Stinchcombe JC, Jenkins MR, de la Roche M, Kleczkowska J, Zamoyska R, Griffiths GM. Tsun A, et al. Among authors: de la roche m. J Cell Biol. 2011 Feb 21;192(4):663-74. doi: 10.1083/jcb.201008140. J Cell Biol. 2011. PMID: 21339332 Free PMC article.

6

IL-7-dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.

Chen HC, Eling N, Martinez-Jimenez CP, O'Brien LM, Carbonaro V, Marioni JC, Odom DT, de la Roche M. Chen HC, et al. Among authors: de la roche m. EMBO Rep. 2019 Aug;20(8):e47379. doi: 10.15252/embr.201847379. Epub 2019 Jul 8. EMBO Rep. 2019. PMID: 31283095 Free PMC article.

7

Aging increases cell-to-cell transcriptional variability upon immune stimulation.

Martinez-Jimenez CP, Eling N, Chen HC, Vallejos CA, Kolodziejczyk AA, Connor F, Stojic L, Rayner TF, Stubbington MJT, Teichmann SA, de la Roche M, Marioni JC, Odom DT. Martinez-Jimenez CP, et al. Among authors: de la roche m. Science. 2017 Mar 31;355(6332):1433-1436. doi: 10.1126/science.aah4115. Science. 2017. PMID: 28360329 Free PMC article.

8

Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.

Hanna J, Beke F, O'Brien LM, Kapeni C, Chen HC, Carbonaro V, Kim AB, Kishore K, Adolph TE, Skjoedt MO, Skjoedt K, de la Roche M, de la Roche M. Hanna J, et al. Among authors: de la roche m. Nat Commun. 2022 Jul 14;13(1):4075. doi: 10.1038/s41467-022-31722-5. Nat Commun. 2022. PMID: 35835905 Free PMC article.

9

Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell.

Thaventhiran JE, Hoffmann A, Magiera L, de la Roche M, Lingel H, Brunner-Weinzierl M, Fearon DT. Thaventhiran JE, et al. Among authors: de la roche m. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):E2223-9. doi: 10.1073/pnas.1209115109. Epub 2012 Jun 27. Proc Natl Acad Sci U S A. 2012. PMID: 22745171 Free PMC article.

10

Hedgehog signaling controls T cell killing at the immunological synapse.

de la Roche M, Ritter AT, Angus KL, Dinsmore C, Earnshaw CH, Reiter JF, Griffiths GM. de la Roche M, et al. Science. 2013 Dec 6;342(6163):1247-50. doi: 10.1126/science.1244689. Science. 2013. PMID: 24311692 Free PMC article.

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