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The FGF-2-derived peptide FREG inhibits melanoma growth in vitro and in vivo.
Aguzzi MS, Faraone D, D'Arcangelo D, De Marchis F, Toietta G, Ribatti D, Parazzoli A, Colombo P, Capogrossi MC, Facchiano A. Aguzzi MS, et al. Among authors: de marchis f. Mol Ther. 2011 Feb;19(2):266-73. doi: 10.1038/mt.2010.211. Epub 2010 Oct 5. Mol Ther. 2011. PMID: 20924364 Free PMC article.
Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction.
Di Maggio S, Milano G, De Marchis F, D'Ambrosio A, Bertolotti M, Palacios BS, Badi I, Sommariva E, Pompilio G, Capogrossi MC, Raucci A. Di Maggio S, et al. Among authors: de marchis f. Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2693-2704. doi: 10.1016/j.bbadis.2017.07.012. Epub 2017 Jul 14. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28716707 Free article.
High mobility group box 1 orchestrates tissue regeneration via CXCR4.
Tirone M, Tran NL, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, Raucci A, Di Maggio S, Santiago C, Mellado M, Saclier M, François S, Careccia G, He M, De Marchis F, Conti V, Ben Larbi S, Cuvellier S, Casalgrandi M, Preti A, Chazaud B, Al-Abed Y, Messina G, Sitia G, Brunelli S, Bianchi ME, Vénéreau E. Tirone M, et al. Among authors: de marchis f. J Exp Med. 2018 Jan 2;215(1):303-318. doi: 10.1084/jem.20160217. Epub 2017 Dec 4. J Exp Med. 2018. PMID: 29203538 Free PMC article.
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4.
Schiraldi M, Raucci A, Muñoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M. Schiraldi M, et al. Among authors: de marchis f. J Exp Med. 2012 Mar 12;209(3):551-63. doi: 10.1084/jem.20111739. Epub 2012 Feb 27. J Exp Med. 2012. PMID: 22370717 Free PMC article.
Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment.
De Leo F, Quilici G, Tirone M, De Marchis F, Mannella V, Zucchelli C, Preti A, Gori A, Casalgrandi M, Mezzapelle R, Bianchi ME, Musco G. De Leo F, et al. Among authors: de marchis f. EMBO Rep. 2019 Oct 4;20(10):e47788. doi: 10.15252/embr.201947788. Epub 2019 Aug 14. EMBO Rep. 2019. PMID: 31418171 Free PMC article.
56 results